The Buffalo Bills (0-2) and Tampa Bay Buccaneers (2-0) face off in NFL Preseason action on Saturday, Aug. 23. Kickoff is set for in 7:30 p.m. ET from Raymond James Stadium in Tampa. The game will broadcast live on NFL+ and ESPN Unlimited.
The Bills are favored by -2.5 with the over/under set at 36.5 total points. Buffalo is a -150 favorite to win outright, while Tampa Bay is +125 to pull off the upset.
Let's get into my Bills vs Buccaneers prediction for Saturday night.
Bills vs Buccaneers Odds
| Bills Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-2.5 -110 | 36.5 -105o / -115u | -150 |
| Buccaneers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+2.5 -110 | 36.5 -105o / -115u | +125 |
- Bills vs Bucs Moneyline: Bills -150, Bucs +125
- Bills vs Bucs Total: 36.5 (-105o / -115u)
- Bills vs Bucs Spread: Bills -2.5 (-110), Bucs +2.5 (-110)
Bills vs Buccaneers NFL Preseason Preview
In NFL preseason, teams coming off a strong but not elite prior season often have deeper rosters and coaching stability, creating hidden value when they enter games as underdogs. This system targets these pedigree teams that won between 9-11 games the previous season, capturing organizations with winning cultures but situational reasons for being slight underdogs in exhibition games.
By isolating only preseason contests, we take advantage of market inefficiencies where public perception and betting lines do not fully account for the depth and preparedness of these rosters.
Backing these underdogs against the spread allows us to capture their edge in execution and depth as they tune up for the regular season, resulting in steady profit despite the unpredictability of preseason outcomes.
Bills quarterback Josh Allen will be sidelined for this game, marking the first time he doesn't play in any preseason game.
Bucs head coach Todd Bowles stated none of his starters will play on Saturday. Veteran Kyle Trask is reportedly likely to get the start with Teddy Bridgewater and Connor Bazelak backing him up.
Pick: Buccaneers +2.5
Spread
Our pick for this game is the Buccaneers to cover the spread.
Moneyline
There is no pick for either side of the moneyline.
Over/Under
There is no pick for the game total.
