Cardinals vs. Broncos Odds & Betting Predictions - August 17, 2025

🔑 Arizona Cardinals ML +152 (FanDuel) 2u The Arizona Cardinals are a strong value play tonight as preseason underdogs, where moneyline upsets historically hit at a higher rate due to teams resting starters and relying on depth players. Arizona comes in at around +152 ML (on FD), offering solid payout potential in a game that will likely be decided by backup execution. With both teams sitting key starters after joint practices, this matchup favors the volatility that often benefits underdogs, and the Cardinals’ roster depth—especially on defense and in skill-position battles—gives them a real chance to capitalize on that preseason trend.