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Chargers vs. Cowboys Odds & Betting Predictions - December 21, 2025

Chargers at Cowboys

6:00 pm • FOX

Los Angeles Chargers

8-4
@

Dallas Cowboys

6-5-1

Chargers at Cowboys Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Chargers
8-4
N/A
N/A
N/A
Cowboys
6-5-1
N/A
N/A
N/A
location pinSunday 6:00 p.m.
December 21, 2025
AT&T StadiumArlington

Chargers vs. Cowboys Props

Prop Projections

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Prop Odds Comparison

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Chargers vs. Cowboys Public Betting Percentages

Away Logo

Chargers

Public

Home Logo

Cowboys

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cowboys are 2-2 in their last 5 games.
  • Cowboys are 4-1 in their last 5 games against the spread
  • Cowboys are 3-3 in their road games against the spread
  • The totals have gone OVER in 4 of Cowboys' last 5 games
  • The totals have gone OVER in 4 of Cowboys' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cowboys		7-54-23-32-45-1
Chargers		6-64-21-45-61-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cowboys		8-44-24-24-24-2
Chargers		6-63-32-35-61-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cowboys		6-5-1N/AN/A3-33-2-1
Chargers		8-4N/AN/A7-41-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 27thKCW 31-28+3.5 WO 53.5DAL +154
Nov 23rdPHIW 24-21+3 WU 48DAL +135
Nov 18th@LVW 33-16-3.5 WO 48.5DAL -199
Nov 4thARIL 17-27-3.5 LU 53.5ARI -175
Oct 26th@DENL 24-44+3.5 LO 51.5DEN +180

Cowboys vs. Chargers Injury Updates

Cowboys Injuries

  • Miles Sanders
    RB

    Sanders is out with ankle

    Out

Chargers Injuries

  • Najee Harris
    RB

    Harris is out with achilles

    Out

  • Hassan Haskins
    RB

    Haskins is out with hamstring

    Out

  • Omarion Hampton
    RB

    Hampton is out with ankle

    Out

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Dak Prescott logo
    Dak Prescott
    3261
    pyds
  • passing touchdowns
    Dak Prescott logo
    Dak Prescott
    25
    ptd
  • rushing yards
    Javonte Williams logo
    Javonte Williams
    955
    ryds
  • rushing touchdowns
    Javonte Williams logo
    Javonte Williams
    8
    rtd
Depth Charts
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Starter2ND3RD4TH
QBDak PrescottJoe MiltonWill Grier
RBJavonte WilliamsJaydon BluePhil MafahMiles SandersMalik Davis
WRCeeDee LambKaVontae TurpinJalen Cropper
TEJake FergusonLuke SchoonmakerBrevyn Spann-FordRivaldo FairweatherPrinceton Fant
LTTyler GuytonNate Thomas
LGTyler SmithT.J. Bass
CCooper BeebeBrock Hoffman
RGTyler Booker
RTTerence SteeleHakeem AdenijiAjani Cornelius
LDEDonovan EzeiruakuSam WilliamsJames Houston
RDEDante FowlerPayton Turner
WLBDeMarvion OvershownMarist LiufauShemar JamesJustin Barron
MLBKenneth MurrayJack Sanborn
LCBTrevon DiggsCaelen Carson
SSMalik HookerMarkquese BellAlijah Clark
FSDonovan WilsonJuanyeh Thomas
RCBDaRon BlandShavon Revel
PBryan Anger
HBryan Anger
PRKaVontae TurpinJalen TolbertJalen Cropper
KRKaVontae TurpinJalen CropperJaydon Blue
LSTrent Sieg
NTOsa OdighizuwaPerrion WinfreyEarnest Brown
DTSolomon ThomasJay Toia
KBrandon Aubrey
LWRGeorge PickensJonathan MingoRyan Flournoy
RWRJalen TolbertTraeshon Holden
FBHunter Luepke
NBZion ChildressJosh ButlerC.J. Goodwin
Team Stats

Passing

2696
YDS
3255
272/409
Comps/Atts
309/446
7.169
YPA
7.534
21/10
TDs/INTs
26/9
40/236
Sacks/Yards
17/105

Rushing

1465
Rush Yards
1462
323
Attempts
315
4.536
YPC
4.641
7
TDs
12

Turnovers

Fumbles Lost
10
Interceptions
9

Efficiency

21/41 51.22%
Redzone
29/48 60.42%
83/172 0%
3rd Down
64/145 0%
9/15 0%
4th Down
9/18 0%

First Downs

244
Total
279
138
Pass
166
85
Rush
78
21
Penalty
35

Misc

/
Penalties/Yards
/
Possession

Chargers vs. Cowboys Odds Comparison

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Chargers at Cowboys Team Totals

MatchupOverUnder
Chargers
8-4
N/A
N/A
Cowboys
6-5-1
N/A
N/A