Giants vs. Patriots Odds, Picks & Thursday Night Football Betting Predictions

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USA Today Sports. Pictured: Josh Gordon, Tom Brady

  • Our staff covers every betting angle of Thursday Night Football featuring the Giants at Patriots, including odds and picks.

Giants at Patriots Odds, Picks & Betting Predictions

  • Odds: Patriots -17
  • Over/Under: 41.5
  • Kickoff: 8:20 p.m. ET
  • TV channel: FOX/NFL Network

Odds as of Thursday afternoon and via PointsBet, where Action Network users can access an exclusive promotion to get a 200% deposit match (deposit $50, bet with $150).


Thursday Night Football Betting Guide

Our analysts and experts break down the most important angles of this game.

Here’s an excerpt, but you can read the full thing here.

This is the fourth time this season the Patriots are favored by more than two touchdowns. So far, they’re 2-1 against the spread in this spot.

Sportsbooks are surely going to be rooting for the Giants to cover, but those prospects got tougher when Saquon Barkley, Wayne Gallman, Sterling Shepard and Evan Engram were ruled out — a cluster of injuries that can impact the spread quite a bit.

Here’s our full betting breakdown for Giants-Patriots here.

Our Favorite Giants vs. Patriots Picks

There’s a lot to considering before betting this Thursday Night Football showdown. Our staff reveals their favorite picks.

Thursday Night Football Weather Forecast

The weather does not look pretty in Foxborough. Here are the latest updates and how it could impact the game.

Best Prop Bets

  • James White’s Rushing Yards
  • Daniel Jones’ Passing Touchdowns
  • Cody Latimer’s Receiving Yards

These are the best player prop bets for Thursday night according to our tools. Here’s how to bet all three.

Fantasy Football Start/Sit Decisions

Start Sony Michel? Sit James White? Sean Koerner runs through all the key lineup decisions for TNF.

DFS Showdown Slate

Cash game strategy. Core GPP plays. Stacks. Chris Raybon breaks down how to play the single-game slate.

TNF Matchup Breakdown

Evan Silva of Establish The Run helps fantasy players and bettors alike understand the game at the deepest level. Read his breakdown for tonight.