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Colorado Avalanche vs St Louis Blues NHL Prediction, Pick, Odds, April 7

Colorado Avalanche vs St Louis Blues NHL Prediction, Pick, Odds, April 7 article feature image
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Isaiah J. Downing-Imagn Images. Pictured: Nazem Kadri passes the puck as Logan Mailloux.

The Colorado Avalanche (50-16-10) and St. Louis Blues (33-31-12) meet in the NHL tonight. Puck drop is set for 8:00 p.m. EDT at Enterprise Center in St. Louis. The game will be broadcast live on ESPN+.

The Avalanche are favored by -1.5 on the puck line, with the over/under set at 6.5 (-105o / -115u). The Avalanche are a -155 favorite to win outright, while the Blues are +130 to pull off the upset.

Let's get into my Avalanche vs. Blues predictions and NHL picks.

Avalanche vs. Blues Odds, Pick

Avalanche Logo
Tuesday, April 7, 2026
8:00 p.m. EDT
ESPN+
Blues Logo
Avalanche Odds
SpreadTotalMoneyline
-1.5
+157
6.5
-105o / -115u
-155
Blues Odds
SpreadTotalMoneyline
+1.5
-190
6.5
-105o / -115u
+130
Odds via FanDuel. Get up-to-the-minute NHL odds here.
FanDuel Logo
  • Avalanche vs. Blues Spread: Avalanche -1.5 (+157), Blues +1.5 (-190)
  • Avalanche vs. Blues Over/Under: 6.5 (-105o / -115u)
  • Avalanche vs. Blues Moneyline: Avalanche -155, Blues +130

Avalanche vs Blues Polymarket Odds

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Avalanche vs. Blues Preview

Colorado Avalanche

The Colorado Avalanche are the best team in hockey and recently became the first team to reach the 50-win mark this season. What makes them so dangerous is their dominance on both ends of the ice.

Entering this matchup, Colorado ranks first in the league in both goals scored per game and goals allowed per game. The Avalanche also take fewer penalties than any other team and, when they do, they kill them off at the highest rate in the league.

Colorado is just as dominant analytically. This season, the Avalanche rank in the top four in expected goals for per 60 minutes (xGF/60), expected goals against per 60 minutes (xGA/60) and expected goal share.

No other team ranks in the top four in all three categories.

St Louis Blues

The St. Louis Blues trail Colorado across the board. They rank behind the Avalanche in xGF/60, xGA/60 and expected goal share.

St. Louis also lags behind Colorado in both goals scored per game and goals allowed per game. One reason the betting line remains relatively close is the Blues’ recent win over the Avalanche on the road Sunday.

However, that result may present a buy-low opportunity on a team that remains superior offensively and defensively. Prior to that game, St. Louis lost 6-1 in its previous meeting against Colorado.

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Avalanche vs. Blues Prediction

Another factor keeping Colorado’s price reasonable is that the Blues are playing at home. However, St. Louis has a sub-.500 record at the Enterprise Center this season.

Colorado, meanwhile, is 26-7-5 on the road. Despite the divisional road matchup, this presents a strong bounce-back opportunity for the Avalanche as they look to avenge Sunday’s loss.

Pick: Avalanche moneyline (-150 | Play to -160)

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