As the favorites for the title begin to take shape and the stars of the season take the reins, each new Premier League matchday brings a surge of betting opportunities.
We have eight games to target on today's EPL schedule, and our staff has come up clutch with four picks to get the ball rolling. Continue reading for our Premier League best bets for Saturday, September 27.
English Premier League Best Bets
The club logos in the table below represent each match that our soccer betting staff is targeting from today's games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Match | Time (ET) | Pick |
|---|---|---|
  | 10:00 a.m. | |
  | 10:00 a.m. | |
  | 12:30 p.m. | |
  | 3:00 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our soccer Odds page, which automatically surfaces the best lines for every game. | ||
AFC Bournemouth vs. Leeds United
By Sam Ingram
The two wins apiece for Leeds and Sunderland from only five games should provide the confidence and belief required to oversee a campaign more successful than the previous six promoted, who were all swiftly relegated.
Leeds' 3-1 victory over Wolves last weekend was a standout result in the division. However, it was against a side currently struggling to return any points after five matches. The team Leeds face next, unfortunately for them, is not of the same ilk as Wolves.
Andoni Iraola’s Bournemouth continues to impress. Only Crystal Palace (9.8xPTS) sits higher than Bournemouth in the expected points table after five games. The Cherries’ 9.3xPTS total is born from their 6.5xG in forward areas, and a stingy 3.6xGA in defense.
The expectation here is that Bournemouth might be too good for Leeds. With the security of the draw on our side in the 'Draw no Bet' market, it could be worth siding with the more established and impressive Premier League club.
Pick: Bournemouth Draw No Bet
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Brighton & Hove Albion vs. Chelsea
By Sam Ingram
Following the 0-0 goalless draw to open the season against Crystal Palace, Chelsea then registered five, two, and two goals in the following three games. The 2-1 loss to Manchester United halted the Blues' run of scoring two or more goals, although that was influenced by goalkeeper Robert Sanchez receiving an early red card.
Next up in the Premier League schedule is Brighton. This is a head-to-head clash that tends to encourage goals. Six consecutive games have witnessed over 2.5 goals for punters. Eight of the most recent meetings between Chelsea and Brighton have encouraged ‘both teams to score – yes’. In 2025/26, both Chelsea (8.4xG) and Brighton (8.1xG) reside in the Premier League’s top five for expected goals.
If early-season trends and the head-to-head data continue on Saturday, this fixture may fall over the 2.5-goal line, with both teams likely to score.
Pick: BTTS – Yes & Over 2.5 Goals
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Sunderland vs. Nottingham Forest
By Sam Ingram
Sunderland, along with fellow promoted sides Burnley and Leeds United, have given a good account of themselves so far this season. This helps explain Nottingham Forest's pricing, which is significantly shorter than last season's promotion class.
Forest’s UEFA Europa League commitments against Real Betis in Seville will have also played a part in the pricing, as will Ange Postecoglou’s rocky start to life in Nottingham. Regardless, Sunderland hasn’t offered much reassurance that they can go to the City Ground and leave with a result. The 0-0 against Crystal Palace was a great result, but they only mustered 0.36xG to Palace’s 1.77xG. A 2-0 defeat to fellow promoted club, Burnley, didn’t reach the 1.0xG total (1.00xG vs 0.77xG).
Still, we shouldn’t expect Sunderland to visit established Premier League clubs and find it easy. Last year’s relegated three won just six of 57 away matches.
Pick: Nottingham Forest Moneyline
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Wolverhampton Wanderers vs. Tottenham
By Sam Ingram
Wolverhampton has its five opening fixtures, the only Premier League team to have failed to return a single point. Analyzing the data, it appears that Wolves have been unlucky. The 12 goals conceded from 7.7xGA, coupled with three scored from 4.4xG, point to underperformance at both ends of the pitch.
Wolves did beat Everton in the EFL Cup on Tuesday, with both teams fielding strong elevens and showing intent to progress to the next round. That might provide Wolves fans with reassurances that results will improve.
However, against Tottenham, away from home, it’s a more daunting trip to face a Thomas Frank side than it was previously. Spurs have lost just once this season after five games, conceding three goals. Only Newcastle (4) has kept more clean sheets than Tottenham’s three in five games.
Pick: Tottenham -1 Handicap
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