Athletics vs. Astros Odds & Betting Predictions - May 28, 2025

Athletics at Astros

6:10 pm • SCHN

Athletics

69-80

3 - 5

Houston Astros

81-68

pitcher		team	era	w-l
L.McCullers			6.88	2-5
L.Severino			4.67	6-11

MatchupOpenSpreadTotalMoneyline
Athletics 69-80	-1.5	+1.5-181	o8.5-101	+120
Astros 81-68	u8.5	-1.5+150	u8.5-120	-142

Wednesday 6:10 p.m.

May 28, 2025

Daikin ParkHouston

HOU -119 (Live)

0.84u

Under 8.5 (Live)-127

ATH +120

🔑 A’s ML +120 (FanDuel) 2u Running it back here. Sharp money strong on this one, 80% of public in the Astros and I like fading the team that just went off the night before. Let’s ride

B.Rooker o0.5 HR+475

0.5u

HOU o4.5 Team Total+106

1.06u

HOU -135

0.74u

Oakland’s spiral is real – lost 12 of 13, including a brutal 11-1 blowout yesterday. Astros red hot at home – 19-10 at Daikin Park, riding 3-game win streak. Altuve hitting .571 last 5 games, 4-hit night yesterday. Team leads MLB in May BA (.280) with 5 straight 11+ hit games. Severino owns a 4.96 ERA vs HOU in 10 career outings – vulnerable vs this lineup. Astros hitters see him well: Altuve .308, Bregman 3 doubles, Tucker homered. Meanwhile, McCullers is trending up – 8 Ks in last outing. Houston bullpen: 2nd in MLB ERA (2.71), 1.11 WHIP, all key arms rested. Oakland pen? 28th in ERA (5.96), wild 4.73 BB/9. Astros also top-10 in fielding%. Add in the Astros’ +54 run differential at home.

ATH +110 (F5)

1.1u

Under 8.5-119

HOU -127

Our 3 MLB Best Bets for Wednesday Night
Action Network Staff•
May 28, 2025 UTC

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No props found

MLB Public Betting

Astros are 3-2 in their last 5 games.
Astros are 4-1 in their last 5 games against the spread
Astros are 42-32 in their road games against the spread
The totals have gone OVER in 1 of Astros' last 5 games
The totals have gone OVER in 32 of Astros' 75 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Astros	76-73	34-41	42-32	39-56	37-15
Athletics	79-70	35-39	44-31	13-21	64-47

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Astros	66-76-7	32-41-2	34-35-5	42-51-2	22-25-5
Athletics	73-69-7	37-35-2	36-34-5	14-18-2	57-49-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Astros	81-68	43-32	38-36	52-43	29-23
Athletics	69-80	32-42	37-38	15-19	51-60

date	opponent	score	spread	over/under	moneyline
May 28th	ATH	W 11-1	-1.5 W	O 8	HOU -245
May 25th	SEA	W 5-3	+1.5 W	U 8.5	HOU +124
May 24th	SEA	W 2-1	+1.5 W	U 7	HOU -108
May 24th	SEA	L 3-5	+1.5 L	U 8.5	SEA -122
May 23rd	SEA	W 9-2	+1.5 W	O 8	HOU +110

Luis Medina
SP
Medina is out with elbow
Out
Tyler Soderstrom
LF
Tyler Soderstrom has been scratched Friday.
Out
Brady Basso
RP
Basso is out with shoulder
Out

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RL.Severino, P	92	6	4	1
RJ.Sterner, P	23	0.2	0	3
RG.Holman, P	17	1.1	1	0

HITTERS	H-AB	R	HR	RBI
1L.Butler, RF	0-4	0	0	0
2J.Wilson, SS	2-3	2	1	2
3B.Rooker, DH	2-4	0	0	1
4T.Soderstrom, LF	0-4	0	0	0
5M.Andujar, 3B	0-4	0	0	0
6S.Langeliers, C	1-4	0	0	0
7C.Alexander, 1B	0-3	0	0	0
7M.Schuemann, PH	0-0	0	0	0
8L.Urias, 2B	1-3	1	0	0
9D.Clarke, CF	0-4	0	0	0

PITCHER	PC	IP	K	ER
RL.McCullers, P	102	6	12	3
RS.Dubin, P	27	1	2	0
RB.Abreu, P	11	1	1	0
LJ.Hader, P	22	1	3	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	1-4	1	0	0
2I.Paredes, 3B	0-2	1	0	1
3J.Altuve, LF	0-4	0	0	0
3C.McCormick, LF	0-0	0	0	0
4C.Walker, 1B	0-1	1	0	0
4M.Dubon, PH	1-2	0	0	0
4M.Dubon, 1B	1-2	0	0	0
4M.Dubon, 2B	1-2	0	0	0
5V.Caratini, C	2-4	0	0	2
5V.Caratini, 1B	2-4	0	0	2
6J.Meyers, CF	0-3	0	0	0
7C.Smith, RF	1-4	0	0	1
8Z.Dezenzo, DH	2-3	2	1	1
9B.Rodgers, 2B	0-2	0	0	0
9Y.Diaz, PH	0-2	0	0	0
9Y.Diaz, C	0-2	0	0	0