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Reds vs. Rays Odds & Betting Predictions - April 22, 2026

Reds at Rays

5:10 pm • RAYS

Cincinnati Reds

16-8
@

Tampa Bay Rays

12-11
Starting Pitchers
pitcherteameraw-l
Nick Martinez logoN.MartinezTampa Bay Rays logo2.460-1
Brandon Williamson logoB.WilliamsonCincinnati Reds logo4.362-1

Reds at Rays Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Reds
16-8
+1.5
+1.5-175
o8.5-110
+119
Rays
12-11
u8
-1.5+145
u8.5-110
-141
location pinWednesday 5:10 p.m.
April 22, 2026
Tropicana FieldSt. Petersburg
Reds vs. Rays Expert Picks
Frank Ammirante
Frank Ammirante
Last 30d: 250-294-14 (-2.8u)
CIN +120
0.83u
Cam Is Money
Cam Is Money
Last 30d: 103-88-3 (+14.1u)
CIN +122
1u
Frank Ammirante
Frank Ammirante
Last 30d: 250-294-14 (-2.8u)
E.De La Cruz o1.5 Hits + Runs + RBIs-114
1.14u
Picks Office
Picks Office
Last 30d: 194-177-7 (+5.2u)
Over 8.5-105
1u
Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy
Doug Ziefel
Doug Ziefel
Last 30d: 277-368-23 (-21.2u)
B.Williamson u15.5 Outs-110
0.55u
Player Prop Savant
Player Prop Savant
Last 30d: 112-85-3 (+14.4u)
E.De La Cruz o1.5 Hits + Runs + RBIs-114
1.14u
RoyalsProps
RoyalsProps
Last 30d: 61-52-6 (+4.3u)
E.De La Cruz o1.5 Hits + Runs + RBIs-110
1.1u
Cam Is Money
Cam Is Money
Last 30d: 103-88-3 (+14.1u)
E.De La Cruz o1.5 Hits + Runs + RBIs-110
1u
Ryan Minion
Ryan Minion
Last 30d: 226-294-4 (-20.7u)
C.Simpson o0.5 Runs Scored+175
$1.00
#ACTION ✍️✍️
C.Simpson o0.5 SB+400
$0.60
#ACTION ✍️✍️
TB -135 (F5)
$1.35
#ACTION ✍️✍️
Anders
Anders
Last 30d: 12-16-2 (-3.7u)
Over 8-110
1.1u
Both starters xERA over 2 runs worse than their actual. Rays pen is a disaster, Reds pen actually just plain ERA wise sits 1st in all of baseball, however that’s just bound to regress. Solid unit, not elite. Just think it’s too low
OldSchool0909
Last 30d: 148-155-0 (+16.8u)
CIN +123
1u
Frank Ammirante
Frank Ammirante
Last 30d: 250-294-14 (-2.8u)
CIN o3.5-120
1.2u
Sean Zerillo
Sean Zerillo
Last 30d: 158-153-12 (-6.8u)
Over 7.5-120
0.6u
Bet to 8 (-115)

Reds vs. Rays Previews & Analysis

  • Minion's SGP for Reds-Rays article feature image

    Minion's SGP for Reds-Rays

    Ryan Minion•
    Apr 22, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Reds vs. Rays Public Betting Percentages

Away Logo

Reds

Public

Home Logo

Rays

61%

Bets%

39%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Rays are 1-4 in their last 5 games.
  • Rays are 1-4 in their last 5 games against the spread
  • Rays are 8-7 in their road games against the spread
  • The totals have gone OVER in 3 of Rays' last 5 games
  • The totals have gone OVER in 5 of Rays' 8 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Rays		12-114-48-76-66-5
Reds		16-86-610-24-212-6

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Rays		15-7-15-310-4-18-3-17-4
Reds		13-10-17-56-5-13-310-7-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Rays		12-114-48-76-66-5
Reds		16-86-610-24-212-6

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 21stCINL 6-12+1.5 LO 7.5CIN -107
Apr 20thCINL 1-6-U 8CIN -126
Apr 19th@PITL 3-6-O 8PIT -112
Apr 18th@PITW 8-7+1.5 WO 7.5TB +131
Apr 17th@PITL 1-5+1.5 LU 8.5PIT +107

Rays vs. Reds Injury Updates

Rays Injuries

  • Gavin Lux
    LF

    Lux is out with shoulder

    Out

  • Michael Grove
    RP

    Grove is out with shoulder

    Out

Reds Injuries

  • Nick Lodolo
    SP

    Lodolo is out with finger

    Out

  • Hunter Greene
    SP

    Greene is out with elbow

    Out

See more MLB Injuries Right Arrow
Reds vs. Rays Starting Lineups
Reds Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Brandon Williamson logoLB.Williamson, P2-14.361.3555.23
HITTERSAVGOBPSLGHR
TJ Friedl logo1T.Friedl, CF.157.263.1810
Matt McLain logo2M.McLain, 2B.198.330.2560
Elly De La Cruz logo3E.De La Cruz, SS.276.343.5718
Sal Stewart logo4S.Stewart, 1B.299.394.6328
Eugenio Suarez logo5E.Suarez, 3B.241.313.3793
Nathaniel Lowe logo6N.Lowe, DH.231.333.3460
Spencer Steer logo7S.Steer, LF.216.289.4324
Will Benson logo8W.Benson, RF.188.333.2810
P.J. Higgins logo9P.Higgins, C.250.333.2500
Rays Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Nick Martinez logoRN.Martinez, P0-12.461.2275.73
HITTERSAVGOBPSLGHR
Yandy Diaz logo1Y.Diaz, DH.322.413.4783
Jonathan Aranda logo2J.Aranda, 1B.229.356.4224
Junior Caminero logo3J.Caminero, 3B.261.349.4575
Ryan Vilade logo4R.Vilade, RF.231.286.3080
Jonny DeLuca logo5J.DeLuca, CF.298.327.5112
Ben Williamson logo6B.Williamson, 2B.241.323.3100
Chandler Simpson logo7C.Simpson, LF.323.351.3660
Nick Fortes logo8N.Fortes, C.305.349.4241
Taylor Walls logo9T.Walls, SS.200.265.2220

Reds vs. Rays Odds Comparison

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Reds at Rays Team Totals

MatchupOverUnder
Reds
16-8
N/A
N/A
Rays
12-11
N/A
N/A