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Guardians vs. Cardinals Odds & Betting Predictions - April 14, 2026

Guardians at Cardinals

11:45 pm • CLEG

Cleveland Guardians

10-7
@

St. Louis Cardinals

8-8
Starting Pitchers
pitcherteameraw-l
Michael McGreevy logoM.McGreevySt. Louis Cardinals logo2.161-1
Joey Cantillo logoJ.CantilloCleveland Guardians logo2.461-0

Guardians at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
10-7
-1.5
-1.5+140
o8.5-101
-120
Cardinals
8-8
u8.5
+1.5-170
u8.5-119
+101
location pinTuesday 11:45 p.m.
April 14, 2026
Busch StadiumSt. Louis
thermometer image82°Fahrenheit
rain image31%Rain
wind image14Wind
Guardians vs. Cardinals Expert Picks
Sean Zerillo
Sean Zerillo
Last 30d: 138-129-5 (-4.3u)
Over 8.5+100
0.5u
Bet to -110

Prop Odds Comparison

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No props found

Line Movement Tracker

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Guardians vs. Cardinals Public Betting Percentages

Away Logo

Guardians

Public

Home Logo

Cardinals

69%

Bets%

31%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Cardinals are 2-3 in their last 5 games.
  • Cardinals are 2-3 in their last 5 games against the spread
  • Cardinals are 3-3 in their road games against the spread
  • The totals have gone OVER in 3 of Cardinals' last 5 games
  • The totals have gone OVER in 6 of Cardinals' 10 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		8-85-53-31-17-7
Guardians		11-65-16-53-08-6

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		9-6-16-43-2-11-18-5-1
Guardians		8-92-46-51-27-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		8-85-53-31-17-7
Guardians		10-74-26-53-07-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 13thCLEL 3-9+1.5 LO 8CLE +100
Apr 12thBOSL 3-9+1.5 LO 9BOS +110
Apr 11thBOSL 1-7+1.5 LO 7.5BOS +118
Apr 11thBOSW 3-2+1.5 WU 7.5STL +115
Apr 8th@WSHW 6-1-1.5 WU 8.5STL -124

Guardians vs. Cardinals Injury Updates

Guardians Injuries

    Cardinals Injuries

    • Lars Nootbaar
      LF

      Nootbaar is out with heel

      Out

    • Hunter Dobbins
      SP

      Dobbins is out with knee

      Out

    See more MLB Injuries Right Arrow
    Guardians vs. Cardinals Starting Lineups
    Guardians Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Joey Cantillo logoLJ.Cantillo, P1-02.461.22712.27
    HITTERSAVGOBPSLGHR
    Steven Kwan logo1S.Kwan, CF.258.343.3391
    Chase DeLauter logo2C.DeLauter, RF.300.379.6805
    Jose Ramirez logo3J.Ramirez, 3B.200.297.3542
    Kyle Manzardo logo4K.Manzardo, 1B.116.224.1861
    Rhys Hoskins logo5R.Hoskins, DH.209.320.3951
    Juan Brito logo6J.Brito, 2B.273.333.3640
    Bo Naylor logo7B.Naylor, C.121.216.1210
    Angel Martinez logo8A.Martinez, LF.319.385.5112
    Brayan Rocchio logo9B.Rocchio, SS.200.344.3402
    Cardinals Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Michael McGreevy logoRM.McGreevy, P1-12.160.7805.40
    HITTERSAVGOBPSLGHR
    JJ Wetherholt logo1J.Wetherholt, 2B.213.329.2791
    Ivan Herrera logo2I.Herrera, DH.193.365.2460
    Alec Burleson logo3A.Burleson, 1B.271.380.4242
    Jordan Walker logo4J.Walker, RF.333.394.7678
    Masyn Winn logo5M.Winn, SS.175.353.2500
    Ramon Urias logo6R.Urias, 3B.233.324.5332
    Jose Fermin logo7J.Fermin, LF.231.267.2310
    Pedro Pages logo8P.Pages, C.194.257.3231
    Victor Scott logo9V.Scott, CF.256.267.2790

    Guardians vs. Cardinals Odds Comparison

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    Guardians at Cardinals Team Totals

    MatchupOverUnder
    Guardians
    10-7
    N/A
    N/A
    Cardinals
    8-8
    N/A
    N/A