Padres vs. Giants Odds & Betting Predictions - May 6, 2026

Padres at Giants

1:45 am • NBCS-BA

San Diego Padres

25-17

10 - 5

San Francisco Giants

18-25

pitcher		team	era	w-l
L.Webb			5.06	2-4
W.Buehler			5.20	2-2

MatchupOpenSpreadTotalMoneyline
Padres 25-17	+1.5	+1.5-172	o7.5-108	+123
Giants 18-25	u7.5	-1.5+145	u7.5-113	-149

Wednesday 1:45 a.m.

May 06, 2026

Oracle ParkSan Francisco

SF +3.5 (Live)+150

0.75u

Under 14.5 (Live)-110

1.1u

Over 7.5 (Live)-109

Under 11.5 (Live)-114

1.14u

Under 11 (Live)-132

1.32u

SF -1.5+165

0.33u

#EV 2.18%

N.Castellanos o0.5 Hits-165

0.73u

#EV 5.82%

R.Devers o1.5 Hits + Runs + RBIs-115

Under 7.5-110

$11.00

SD +110

1.1u

Under 7.5-115

0.5u

@Zerillo ⭐️⭐️ https://myaction.app/JSRRLRwFT2b

W.Buehler o3.5 Ks-110

0.5u

Under 7.5-115

0.58u

Bet to -125 or 7 (-102)

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No props found

MLB Public Betting

Giants are 3-2 in their last 5 games.
Giants are 2-3 in their last 5 games against the spread
Giants are 9-12 in their road games against the spread
The totals have gone OVER in 3 of Giants' last 5 games
The totals have gone OVER in 10 of Giants' 22 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	18-25	9-13	9-12	5-10	13-14
Padres	23-19	13-10	10-9	13-12	10-7

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	18-23-2	10-11-1	8-12-1	10-5	7-18-2
Padres	17-24-1	10-12-1	7-12	9-15-1	8-9

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	18-25	10-12	8-13	7-8	11-16
Padres	25-17	13-10	12-7	15-10	10-7

date	opponent	score	spread	over/under	moneyline
May 5th	SD	W 3-2	+1.5 W	U 8	SF +112
May 3rd	@TB	L 1-2	+1.5 W	U 8	TB +104
May 2nd	@TB	L 1-5	-1.5 L	U 7.5	TB -115
May 1st	@TB	L 0-3	+1.5 L	U 7.5	TB +117
Apr 30th	@PHI	L 5-6	+1.5 W	O 8.5	PHI +119

Hayden Birdsong
SP
Birdsong is out with arm
Out

Joe Musgrove
SP
Musgrove is out with elbow
Out
Will Wagner
3B
Wagner is out with oblique
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RW.Buehler, P	82	5.1	5	4
RJ.Estrada, P	21	1.2	2	1
RJ.Adam, P	9	1	0	0
RR.Marinaccio, P	9	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Merrill, CF	3-5	2	0	2
2M.Machado, 3B	0-5	0	0	0
3M.Andujar, DH	3-5	1	0	1
4G.Sheets, 1B	2-5	1	0	0
5F.Tatis, RF	1-5	1	0	0
6X.Bogaerts, SS	2-4	1	1	2
7N.Castellanos, LF	1-3	1	0	2
7B.Johnson, LF	0-1	0	0	0
8L.Campusano, C	0-2	1	0	0
9S.Song, 2B	2-4	2	0	2

PITCHER	PC	IP	K	ER
RL.Webb, P	62	4	4	6
RJ.Brubaker, P	38	1	1	1
LR.Borucki, P	20	1	0	1
RG.Santos, P	28	2	0	2
RJ.Peguero, P	8	1	0	0

HITTERS	H-AB	R	HR	RBI
1J.Lee, RF	1-4	1	0	1
2C.Schmitt, 2B	1-4	1	1	2
3R.Devers, 1B	1-4	0	0	0
4H.Ramos, LF	0-4	0	0	0
5B.Eldridge, DH	1-4	0	0	0
6M.Chapman, 3B	0-4	0	0	0
7W.Adames, SS	1-4	1	0	0
8D.Gilbert, CF	1-3	1	0	0
8C.Koss, PH	0-1	0	0	0
9J.Rodriguez, C	2-3	1	1	2