Padres vs. Giants Odds & Betting Predictions - May 6, 2026

Padres at Giants

1:45 am • NBCS-BA

San Diego Padres

32-24

10 - 5

San Francisco Giants

22-35

pitcher		team	era	w-l
L.Webb			4.82	2-4
W.Buehler			4.88	3-3

MatchupOpenSpreadTotalMoneyline
Padres 32-24	+1.5	+1.5-172	o7.5-108	+123
Giants 22-35	u7.5	-1.5+145	u7.5-113	-149

Wednesday 1:45 a.m.

May 06, 2026

Oracle ParkSan Francisco

SF +3.5 (Live)+150

0.75u

Under 14.5 (Live)-110

1.1u

Over 7.5 (Live)-109

Under 11.5 (Live)-114

1.14u

Under 11 (Live)-132

1.32u

R.Devers o1.5 Hits + Runs + RBIs-115

SD +110

1.1u

Under 7.5-115

0.5u

@Zerillo ⭐️⭐️ https://myaction.app/JSRRLRwFT2b

W.Buehler o3.5 Ks-110

0.5u

Under 7.5-115

0.58u

Bet to -125 or 7 (-102)

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No props found

MLB Public Betting

Giants are 1-4 in their last 5 games.
Giants are 2-3 in their last 5 games against the spread
Giants are 11-18 in their road games against the spread
The totals have gone OVER in 3 of Giants' last 5 games
The totals have gone OVER in 14 of Giants' 28 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	23-34	12-16	11-18	7-13	16-20
Padres	32-24	18-14	14-10	15-13	17-11

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	27-27-3	14-12-2	13-15-1	14-5-1	12-22-2
Padres	23-32-1	12-19-1	11-13	10-17-1	13-15

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	22-35	12-16	10-19	9-11	13-23
Padres	32-24	16-16	16-8	16-12	16-12

date	opponent	score	spread	over/under	moneyline
May 5th	SD	W 3-2	+1.5 W	U 8	SF +112
May 3rd	@TB	L 1-2	+1.5 W	U 8	TB +104
May 2nd	@TB	L 1-5	-1.5 L	U 7.5	TB -116
May 1st	@TB	L 0-3	+1.5 L	U 7.5	TB +117
Apr 30th	@PHI	L 5-6	+1.5 W	O 8.5	PHI +118

Hayden Birdsong
SP
Birdsong is out with arm
Out

Joe Musgrove
SP
Musgrove is out with elbow
Out
Will Wagner
3B
Wagner is out with oblique
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RW.Buehler, P	82	5.1	5	4
RJ.Estrada, P	21	1.2	2	1
RJ.Adam, P	9	1	0	0
RR.Marinaccio, P	9	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Merrill, CF	3-5	2	0	2
2M.Machado, 3B	0-5	0	0	0
3M.Andujar, DH	3-5	1	0	1
4G.Sheets, 1B	2-5	1	0	0
5F.Tatis, RF	1-5	1	0	0
6X.Bogaerts, SS	2-4	1	1	2
7N.Castellanos, LF	1-3	1	0	2
7B.Johnson, LF	0-1	0	0	0
8L.Campusano, C	0-2	1	0	0
9S.Song, 2B	2-4	2	0	2

PITCHER	PC	IP	K	ER
RL.Webb, P	62	4	4	6
RJ.Brubaker, P	38	1	1	1
LR.Borucki, P	20	1	0	1
RG.Santos, P	28	2	0	2
RJ.Peguero, P	8	1	0	0

HITTERS	H-AB	R	HR	RBI
1J.Lee, RF	1-4	1	0	1
2C.Schmitt, 2B	1-4	1	1	2
3R.Devers, 1B	1-4	0	0	0
4H.Ramos, LF	0-4	0	0	0
5B.Eldridge, DH	1-4	0	0	0
6M.Chapman, 3B	0-4	0	0	0
7W.Adames, SS	1-4	1	0	0
8D.Gilbert, CF	1-3	1	0	0
8C.Koss, PH	0-1	0	0	0
9J.Rodriguez, C	2-3	1	1	2