Padres vs. Giants Odds & Betting Predictions - May 6, 2026

Padres at Giants

1:45 am • NBCS-BA
10 - 5
Starting Pitchers
pitcherteameraw-l
Logan Webb logoL.WebbSan Francisco Giants logo4.822-4
Walker Buehler logoW.BuehlerSan Diego Padres logo4.883-3

Padres at Giants Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
32-24
+1.5
+1.5-172
o7.5-108
+123
Giants
22-35
u7.5
-1.5+145
u7.5-113
-149
location pinWednesday 1:45 a.m.
May 06, 2026
Oracle ParkSan Francisco
Padres vs. Giants Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 145-119-2 (+19.7u)
SF +3.5 (Live)+150
0.75u
Under 14.5 (Live)-110
1.1u
Over 7.5 (Live)-109
1u
Under 11.5 (Live)-114
1.14u
Under 11 (Live)-132
1.32u
Cam Is Money
Cam Is Money
Last 30d: 56-75-2 (-25.5u)
R.Devers o1.5 Hits + Runs + RBIs-115
1u
Kev Mahserejian
Kev Mahserejian
Last 30d: 10-9-0 (+4.8u)
SD +110
1.1u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 83-107-11 (-9.5u)
Under 7.5-115
0.5u
@Zerillo ⭐️⭐️ https://myaction.app/JSRRLRwFT2b
Doug Ziefel
Doug Ziefel
Last 30d: 184-147-4 (+16.0u)
W.Buehler o3.5 Ks-110
0.5u
Sean Zerillo
Sean Zerillo
Last 30d: 176-148-11 (+5.3u)
Under 7.5-115
0.58u
Bet to -125 or 7 (-102)

Padres vs. Giants Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Padres vs. Giants Public Betting Percentages

Away Logo

Padres

Public

48%

Bets%

52%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Giants
23-3412-1611-187-1316-20
Padres
32-2418-1414-1015-1317-11

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Giants
27-27-314-12-213-15-114-5-112-22-2
Padres
23-32-112-19-111-1310-17-113-15

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Giants
22-3512-1610-199-1113-23
Padres
32-2416-1616-816-1216-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 5thSDW 3-2+1.5 WU 8SF +112
May 3rd@TBL 1-2+1.5 WU 8TB +104
May 2nd@TBL 1-5-1.5 LU 7.5TB -116
May 1st@TBL 0-3+1.5 LU 7.5TB +117
Apr 30th@PHIL 5-6+1.5 WO 8.5PHI +118

Giants vs. Padres Injury Updates

Giants Injuries

  • Hayden Birdsong
    SP

    Birdsong is out with arm

    Out

Padres Injuries

  • Joe Musgrove
    SP

    Musgrove is out with elbow

    Out

  • Will Wagner
    3B

    Wagner is out with oblique

    Out

Padres vs. Giants Box Score
Padres Player Stats
Projected
PITCHERPCIPKER
Walker Buehler logoRW.Buehler, P825.154
Jeremiah Estrada logoRJ.Estrada, P211.221
Jason Adam logoRJ.Adam, P9100
Ron Marinaccio logoRR.Marinaccio, P9110
HITTERSH-ABRHRRBI
Jackson Merrill logo1J.Merrill, CF3-5202
Manny Machado logo2M.Machado, 3B0-5000
Miguel Andujar logo3M.Andujar, DH3-5101
Gavin Sheets logo4G.Sheets, 1B2-5100
Fernando Tatis logo5F.Tatis, RF1-5100
Xander Bogaerts logo6X.Bogaerts, SS2-4112
Nick Castellanos logo7N.Castellanos, LF1-3102
Bryce Johnson logo7B.Johnson, LF0-1000
Luis Campusano logo8L.Campusano, C0-2100
Sung Mun Song logo9S.Song, 2B2-4202
Giants Player Stats
Projected
PITCHERPCIPKER
Logan Webb logoRL.Webb, P62446
JT Brubaker logoRJ.Brubaker, P38111
Ryan Borucki logoLR.Borucki, P20101
Gregory Santos logoRG.Santos, P28202
Joel Peguero logoRJ.Peguero, P8100
HITTERSH-ABRHRRBI
Jung Hoo Lee logo1J.Lee, RF1-4101
Casey Schmitt logo2C.Schmitt, 2B1-4112
Rafael Devers logo3R.Devers, 1B1-4000
Heliot Ramos logo4H.Ramos, LF0-4000
Bryce Eldridge logo5B.Eldridge, DH1-4000
Matt Chapman logo6M.Chapman, 3B0-4000
Willy Adames logo7W.Adames, SS1-4100
Drew Gilbert logo8D.Gilbert, CF1-3100
Christian Koss logo8C.Koss, PH0-1000
Jesus Rodriguez logo9J.Rodriguez, C2-3112

Padres vs. Giants Odds Comparison

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Padres at Giants Team Totals

MatchupOverUnder
Padres
32-24
N/A
N/A
Giants
22-35
N/A
N/A