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White Sox vs Yankees Prediction, Pick, Odds, for Wednesday, September 24

White Sox vs Yankees Prediction, Pick, Odds, for Wednesday, September 24 article feature image
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Photo by Mark Smith-Imagn Images. Pictured: Max Fried

The New York Yankees host the Chicago White Sox on September 24, 2025. First pitch from Yankee Stadium is scheduled for 7:05 p.m. EDT; the game will be broadcast on CHSN.

The Yankees won the series opener 3-2 and will have Max Fried on the hill tonight against the White Sox.

Find my MLB betting preview and White Sox vs Yankees prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My White Sox vs Yankees Prediction

  • White Sox vs Yankees pick: Under 8 (-105)

My White Sox vs Yankees best bet is Under 8 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


White Sox vs Yankees Odds

White Sox Logo
Wednesday, Sep 24
7:05 p.m. ET
CHSN
Yankees Logo
White Sox Odds
SpreadTotalMoneyline
+1.5
+140
8
-115o / -105u
+290
Yankees Odds
SpreadTotalMoneyline
-1.5
-160
8
-115o / -105u
-380
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo

White Sox vs Yankees Projected Starting Pitchers

LHP Fraser Ellard (CHW)StatLHP Max Fried (NYY)
0-2W-L18-5
0.0fWAR (FanGraphs)4.5
4.50 / 5.42ERA / xERA2.92 / 3.49
4.65 / 4.89FIP / xFIP3.12 / 3.41
1.50WHIP1.11
5.9K-BB%17.2
41.9GB%52.5
100Stuff+111
88Location+102

White Sox vs Yankees Preview

Max Fried is finishing the season strong. The Yankees starter is coming off a seven-inning scoreless outing against the Orioles, in which he struck out 13 batters and gave up just three hits.

Fried has a 2.84 ERA across his last seven starts, and his home split bodes well for this contest, as he holds a 2.46 ERA at Yankee Stadium.

The White Sox have one of the worst offenses this year, ranking 27th in wRC+ (88).

The first game of this series already hit the under with just five runs total, and our Bet Labs system has a weather angle that recommends going for it again.

MLB Icon
Evan Abrams / Bet Labs – Public Fades Humidity = Unders
the average humidity is between 45% and 95%
the home team's 5 Game over percentage is between 0% and 40%
the temperature is between 54 and 97 degrees
the wind direction is From Right or Left To Right or From Left or Right To Left or In or None
the o/u change from open to close is between -1 and 0
the over/under % is between 6% and 29%
the game was played during the 2025 or 2024 or 2023 or 2022 or 2021 or 2020 season
betting on the Under
the game is played during the Regular season
$8,192
WON
341-235-21
RECORD
59%
WIN%

This system capitalizes on an overlooked weather edge in MLB totals betting. It focuses on regular-season games where elevated humidity — ranging from 45 to 95 — intersects with moderate temperatures and neutral wind patterns.

Despite assumptions that humidity boosts offense, public bettors are fading these conditions, which actually correlate with suppressed scoring in certain environments.

In these spots, the home team has stayed under in recent games, with their five-game over rate sitting below 40, suggesting low offensive rhythm.

The market has also subtly corrected, with the total dropping from open to close, and the overall percentage of bets on the over remains modest, between 6 and 29. These indicators combine to identify under-the-radar under spots where public narratives misalign with actual scoring trends.

Pick: Under 8 (-105, bet365)


White Sox vs Yankees Betting Trends


White Sox vs Yankees Weather


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