The Arizona Diamondbacks host the Los Angeles Dodgers on September 25, 2025. First pitch from Chase Field is scheduled for 3:40 p.m. EDT; the game will be broadcast on SportsNet LA.
After splitting the first two games, this series finale will feature the Dodgers' Yoshinobu Yamamoto and the Diamondbacks' Jalen Beeks on the mound.
Find my MLB betting preview and Dodgers vs Diamondbacks prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Dodgers vs Diamondbacks Prediction
- Dodgers vs Diamondbacks pick: Over 8.5 (-105)
My Dodgers vs Diamondbacks best bet is Over 8.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Dodgers vs Diamondbacks Odds
| Dodgers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +110 | 8.5 -105o / -115u | -160 |
| Diamondbacks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -130 | 8.5 -105o / -115u | +135 |
Dodgers vs Diamondbacks Projected Starting Pitchers
| RHP Yoshinobu Yamamoto (LAD) | Stat | LHP Jalen Beeks (ARI) |
|---|---|---|
| 11-8 | W-L | 5-2 |
| 4.7 | fWAR (FanGraphs) | 0.3 |
| 2.58 / 2.70 | ERA / xERA | 3.67 / 3.69 |
| 2.99 / 3.05 | FIP / xFIP | 3.83 / 4.26 |
| 0.99 | WHIP | 1.08 |
| 20.8 | K-BB% | 11.5 |
| 52.5 | GB% | 47.1 |
| 98 | Stuff+ | 95 |
| 110 | Location+ | 90 |
Dodgers vs Diamondbacks Preview
The first two games of this series finished with the same exact total and score: nine runs (5-4). That was even with great outings from the Dodgers' Shohei Ohtani and Blake Snell, and quality starts from the Diamondbacks' Ryne Nelson and Brandon Pfaadt.
So that means both lineups are more than capable of hitting each other's relief corps. Arizona's bullpen ranks 27th in the majors with a 4.81 ERA, and Los Angeles is not far, sitting at 22nd (4.34).
The Dodgers have the third-best offense in wRC+ (113) this season, while the Diamondbacks are 7th with a 109 wRC+ rating.
Plus, Arizona will send reliever Jalen Beeks to the mound, in what will only be his second start this season. The lefty will probably be followed by several of his bullpen teammates.
This aligns with our Bet Labs recommendation to stay with the over for this series finale.
Late in the MLB season, games played in hitter-friendly or high-variance environments — such as in Colorado, Arizona, and Washington — tend to go over the total when the closing line is modest (≤10.5).
These markets often underestimate run production during the final stretch of the season due to weather conditions (e.g., dry heat in AZ/CO, humid air in DC) and expanded rosters increasing bullpen volatility.
Public perception around fatigue or playoff pressure may further depress totals.
This creates value when betting overs in August to October for these specific home teams, particularly during regular-season games.
Pick: Over 8.5 (-105, bet365)
Dodgers vs Diamondbacks Betting Trends
