The Arizona Diamondbacks (80-77) host the Los Angeles Dodgers (88-69) on September 24, 2025. First pitch from Chase Field is scheduled for 9:40 p.m. EDT; the game will be broadcast on ARID.
Find my MLB betting preview and Dodgers vs Diamondbacks prediction below, as well as probable pitchers, betting trends, injury reports and more.
Our Dodgers vs Diamondbacks Prediction
- Dodgers vs Diamondbacks pick: Over 8.5
Our Dodgers vs Diamondbacks best bet is on the over total runs. Make sure to find the best odds by checking our live MLB odds page.
Dodgers vs Diamondbacks Odds
| Dodgers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +110 | 8.5 -110o / -110u | -150 |
| Diamondbacks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -130 | 8.5 -110o / -110u | +125 |
Dodgers vs Diamondbacks Projected Starting Pitchers
| LHP Blake Snell (LAD) | Stat | RHP Ryne Nelson (ARI) |
|---|---|---|
| 5-4 | W-L | 7-3 |
| 1.6 | fWAR (FanGraphs) | 1.8 |
| 2.44/3.24 | ERA /xERA | 3.34/3.94 |
| 2.78/3.10 | FIP / xFIP | 3.80/4.14 |
| 1.28 | WHIP | 1.07 |
| 18.2% | K-BB% | 13.8% |
| 46.6% | GB% | 40.7% |
| 98 | Stuff+ | 108 |
| 113 | Location+ | 100 |
Dodgers vs Diamondbacks Prediction, Betting Analysis
The Los Angeles Dodgers are a -150 favorite to win outright on the moneyline, while the Arizona Diamondbacks are +125 underdogs. The total is set at 8.5 runs.
This is Game 2 of the series after Arizona pulled off a 5-4 walk-off win in Game 1. Geraldo Perdomo delivered the game-winning single in the ninth inning as the D-backs rallied from an early four-run deficit. The victory kept Arizona within one game of the New York Mets for the final NL wild-card spot, tied with the Cincinnati Reds. Meanwhile, the Dodgers’ NL West lead is down to just 1.5 games over the Padres.
On the mound, Blake Snell gets the ball for Los Angeles. Snell has been historically dominant in September, becoming the first pitcher since Cy Young in 1905 to record consecutive starts with 11+ strikeouts, 2 or fewer hits, 2 or fewer walks, and no runs allowed. Arizona counters with Ryne Nelson, who has quietly been sharp this month with a 2.35 ERA and 15 strikeouts across four September starts.
While the pitching matchup looks strong on paper, the value sits with the total. This game checks a key angle from Evan Abrams’ “Late Season Overs, Lower Totals” system. Late in the MLB season, hitter-friendly or high-variance environments like Arizona often push games over modest totals (≤10.5).
With dry desert air, bullpen volatility from expanded rosters, and playoff pressure amplifying mistakes, these matchups tend to see more offense than the market expects.
Even with Snell and Nelson dealing well of late, the conditions point toward runs piling up again after the 5-4 opener.
Pick: Over 8.5 (-110, bet365)
Dodgers vs Diamondbacks Betting Trends
