Brewers vs Reds Prediction, Pick, Odds for Friday, August 15

Brewers vs Reds Prediction, Pick, Odds for Friday, August 15 article feature image
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Credit: Imagn Images. Pictured: Cincinnati Reds SP Nick Martinez.

The Cincinnati Reds host the Milwaukee Brewers on August 15, 2025. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT; the game will be broadcast on Apple TV+.

The Brewers will look to extend their winning streak to a season-high 13 games as they begin a road trip to Cincinnati.

Read our Brewers vs Reds prediction and MLB pick below.

Quickslip

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My Brewers vs Reds Prediction

  • Brewers vs Reds Picks: Reds ML (+100 or better)

My Brewers vs Reds best bet is on the Reds. Make sure to find the best odds by checking our live MLB odds page.


Brewers vs Reds Odds

Brewers Logo
August 15, 2025
6:40 p.m. EDT
Apple TV+
Reds Logo
Brewers Odds
SpreadTotalMoneyline
-1.5
+116
9
-122 / +101
-145
Reds Odds
SpreadTotalMoneyline
+1.5
-141
9
-122 / +101
+119
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

Brewers vs Reds Projected Starting Pitchers

RHP Jacob Misiorowski (MIL)StatRHP Nick Martinez (CIN)
4-1W-L10-9
0.8fWAR (FanGraphs)2.1
2.70 / 2.25ERA / xERA4.49 / 4.08
3.11 / 2.82FIP / xFIP4.12 / 4.41
0.96WHIP1.19
3.4K-BB%2.9
39.7GB%37.8
118Stuff+87
104Location+109

Sean Paul’s Brewers vs Reds Preview

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Milwaukee Brewers Betting Preview

The Miz is Back, more than likely.

The Brewers haven't announced a starter for Friday, but all signs point to the very electrifying rookie, Jacob Misiorowski, returning after a brief two-week stint on the injured list with a left tibia contusion.

The couple of weeks' layoff produces an interesting set of circumstances.

For one, Misiorowski will likely not have a full workload due to the layoff. With a lengthy lead in the NL Central, it’s unlikely the Brewers want to push their prized young starter to an uncomfortable pitch count.

There’s no denying Misiorowski's talent. He's pitching to a strong 2.70 with a 2.25 xERA, 3.11 FIP, and 12.69 K/9. Typically, the Miz doesn't go super deep in games. That's partially a byproduct of his swing-and-miss stuff leading to deeper pitch counts. In his seven big league outings, he's pitched just 33 2/3 innings.

So, the Reds will aim to work his pitch count and get to the bullpen sooner rather than later.

Milwaukee might lack top-end home run power, but its ability to put the ball in play makes for an elite offense. The Brewers have a 140 wRC+ across their past 24 games, which puts them only behind the Blue Jays. Those are the only two teams with an average above .276, as the Blue Jays are hitting .306 and Milwaukee is hitting .301.


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Cincinnati Reds Betting Preview

The Reds are right in the mix for a playoff spot. They trail the Mets by 0.5 games for the final Wild Card spot in the National League. So, it's safe to say this series has a lot of stakes for the home team.

There's a strong contrast in pure stuff between Misiorowski and Reds starter Nick Martinez. But I actually think Martinez could do well versus a Brewers team that puts the ball in play as frequently as they do.

While Martinez enters this outing with a 4.49 ERA, he has a 4.08 xERA and 4.12 FIP. If there is regression, it probably won't be anything crazy. But he shouldn't implode and finish his 2025 with an ERA nearing 5.00.

So, what makes Martinez a potential weapon here? He throws strikes, ranking in the 85th percentile among qualified pitchers in walk rate, and sits in the 83rd percentile in hard-hit rate allowed.

He's also been terrific across his past five starts, pitching at least five innings with two or fewer runs in each outing. Martinez can go a strong six innings here and hand the ball to Graham Ashcraft, Tony Santillan, and Emilio Pagan to seal the deal.

Despite winning recently, its offense hasn't done them any favors. In 25 games since the All-Star break, the Reds rank 27th among MLB lineups with a 90 wRC+. However, they could force Misiorowski into deep pitch counts with their strong 8.5% walk rate.

The addition of Miguel Andujar is saving the Reds' offense from being the absolute worst in the league. The trade deadline addition from the Athletics is hitting .370 with a 236 wRC+, including a grand slam in Cincinnati's last game versus the Phillies.

What they'll need to change is Elly De La Cruz posting an 80 wRC+ in 25 games. He's supposed to be the engine that makes this Reds team go, and he's been the anchor dragging the offense down lately.


Brewers vs Reds Prediction, Betting Analysis

The good thing, if you're with me in backing the Reds here, is that they continue to win even without Elly playing well. It'll make a huge difference if that changes.

The Brewers have won 12 straight games, but all good things must come to an end. They won't win every game for the rest of the year, and Martinez has the right attack to limit an exciting Milwaukee offense.

I'll take the plus money with the Reds at home.

Pick: Reds ML (+100 or better)


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About the Author
Sean is a contributor for the Action Network college basketball and baseball verticals, focusing on bringing insightful, in-depth betting analysis. Sean started his writing career talking about college hoops, with a strong focus on mid-major hoops, which he still covers.

Follow Sean Paul @seanpaulcbb on Twitter/X.

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