Saturday is an incredible day for gambling.
We have a full 15-game MLB slate starting in the early afternoon and rolling directly into the Final Four games at night.
Start your day off right with our MLB Picks and Predictions for Saturday, April 4.
MLB Picks, Predictions
The team logos in the table below represent the matchups our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 2:10 PM | |
  | 4:10 PM | |
  | 7:15 PM | |
  | 9:38 PM | |
 | All Day | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Brewers vs. Royals Moneyline Picks
By Sean Paul
Everything here points towards the Brewers.
Starting pitcher Luinder Avila is unknown, and relievers will likely have to cover five or six innings — a bullpen that I already don't trust.
Plus, the Brewers' lineup is flat-out better.
Milwaukee is a great play in this spot.
Read Paul's full Brewers-Royals breakdown here:
Pick: Brewers ML (-130 or Better)
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Padres vs. Red Sox Over/Under Picks
This game triggered one of our Action PRO Betting systems, powered by Evan Abrams.
Weather Watch Unders is a system built for MLB totals bettors who understand how environmental factors quietly shift run production.
This approach keys in on games with moderate to strong winds — especially those blowing in or cross-field — paired with mild to cool temperatures, a known recipe for stifled fly balls and reduced scoring.
When totals open high, but tick down before the first pitch, it signals sharp money reacting to these same weather cues.
With home moneyline ranges excluding extreme mismatches, the model focuses on contests where weather can truly swing scoring.
Layered into regular-season motivation, this strategy captures overlooked market inefficiencies in totals inflated by prior offensive output rather than by field conditions.
The weather report for Fenway is much worse than I imagined when I saw this system pop up.
We are looking at temperatures in the high-30s to low-40s with double-digit winds blowing straight in toward home plate from right field. Given these conditions, BallParkPal has projected a -14% run-scoring factor behind a -48% home-run factor.
Boston is going to see some intense pitcher-friendly weather on Saturday. I don't even care who's pitching, I'm taking the Under — although it's worth mentioning that I'm high on Connelly Early, while the Padres' loaded bullpen is fully rested after Friday's loss.
Want more Bet Labs systems? Download the Action Network App and sign up for an Action PRO Subscription here:
Pick: Under 7.5 (+100 or Better)
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Braves vs. Diamondbacks Moneyline Picks
The big question mark in the Diamondbacks' rotation is Michael Soroka.
The former top prospect, who has since torn his Achilles twice, was masterful in his first start. Soroka pitched five innings, gave up four hits, zero ER, zero walks, and struck out 10 batters.
The only red flag on Soroka's outing was a 5.35 xERA, which indicates significant hard contact. Nevertheless, this was his first start of the season, and there was much more good than bad.
Despite his 4.70 ERA, Michael Soroka had similar success in the first half of 2025. He pitched 59 1/3 innings from March to June, with a 3.23 xERA and 3.88 xFIP. He missed time in April and May due to a biceps strain, but that did not stop him from taking a step in his career.
2025 represented Soroka's best season since his lone full season in 2019 with the Braves. He was transferred to the bullpen after struggling in July and dealt with a shoulder injury later in the year, but there was a significant bright spot.
Meanwhile, Bryce Elder is still Bryce Elder, an innings-eating starter the Braves do not want to start, but have to. Elder's first game of the season went smoothly with zero runs allowed through six innings against the Athletics.
The Athletics' offense is talented, but they are better at home in their bandbox minor league stadium than on the road. Their home wOBA in 2025 was .331, while their away wOBA was .317.
Elder has plateaued as a mediocre pitcher since 2024, even with a one MPH jump in fastball velocity since 2025. He has league-average peripherals in his 4.02 xFIP and 4.25 SIERA from 2024 through 2025, but his xERA is a horrendous 4.77.
Elder will face an easier lineup this week than last week, but luck cannot be on his side every start. Until Ronald Acuna Jr. gets going, the Braves' offense may not be enough to overcome the hole that starters like Elder dig them into.
Read Kev's full Braves-Snakes breakdown here:
Pick: Diamondbacks ML (-110 or Better)
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Mariners vs. Angels Team Total Picks
By Matt Trollo
Jack Kochanowicz generally has more Ks in his name than his box score, so it was a bit stunning when he sent down even three of 22 Astros in his first start. He still surrendered more walks (five) and runs (six).
Batters from either side of the plate are within a .359 to .393 wOBA and xwOBA against JK since last season, and he doesn’t have a single estimator below five over that span. This includes a 5.22 Pitching Bot ERA.
The Mariners had a team 116 wRC+ on the road last year and get a significant park upgrade with the expectation of some beautiful hitting weather with a forecast of 80 degrees plus 10 mph winds out to CF. Angel Stadium is already an extremely power-friendly, positive-run environment (102 Park Run Factor) on a neutral day.
Seattle’s projected lineup averages a 127 wRC+ against RHP since last season. Cal Raleigh destroys sinkers (5.9 wSI/C), a pitch that Kochanowicz throws 46.7% of the time. In fact, he doesn’t have a single pitch level matchup (using run values) in his favor in this lineup.
If you need any additional incentive, the Angels may have the worst defense (proj. LU -47 Fielding Run Value last year) along with one of the worst bullpens (4.29 FIP Fangraphs projection) in the league.
Some books are offering 5.5 at plus money, but FanDuel is offering the price below at the time of writing.
Read Trollo's full Opening Pitch card for Saturday here:
Pick: Mariners TT Over 4.5 (-165 or Better)
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Zerillo's Full Action App Card for Saturday
Need more picks for Saturday? It's always wise to see what our guy Sean Zerillo is betting on!
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