The Chicago Cubs host the San Diego Padres on June 29, 2026. First pitch from Wrigley Field is scheduled for 8:05 p.m. EDT. The game will be broadcast on SDPA.
The Cubs are favored by -154 on the moneyline and by -1.5 on the run line. The Padres are +125 on the moneyline and +1.5 on the run line. The total is set at 11 runs.
Find my MLB picks and Padres vs Cubs prediction below, as well as probable pitchers, weather report, and more.
Padres vs Cubs Prediction
- Padres vs Cubs Pick: Nothing specific, but go shopping for advantageous home run lines
My Padres vs Cubs best bet is to shop for a good HR line. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Cubs Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +125 | 11 -110o / -111u | +125 |
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -150 | 11 -110o / -111u | -154 |
- Padres vs Cubs moneyline: Padres +125, Cubs -154
- Padres vs Cubs over/under: 11 (-110o / -111u)
- Padres vs Cubs spread: Cubs -1.5 (+125 ), Padres +1.5 (-150)
Padres vs Cubs Probable Pitchers
| RHP Griffin Canning (SDP) | Stat | LHP Shota Imanaga (CHC) |
|---|---|---|
| 1-5 | W-L | 5-6 |
| -0.1 | fWAR (FanGraphs) | 0.6 |
| 7.38/5.18 | ERA / xERA | 4.40 3.65 |
| 5.42/4.48 | FIP / xFIP | 4.86 3.96 |
| 8.9% | K-BB% | 17.6% |
| 47.9% | GB% | 36.8% |
| .327 | BABIP | .230 |
| 89 | Stuff+ | 93 |
| 90 | Location+ | 109 |
Padres vs Cubs MLB Betting Preview
WRIGLEY WINDS ALERT. We have this game +19% in run scoring due to the weather situation. The books are pretty sharp at accounting for this stuff, and the game total is 11.5.
It's Griffin Canning vs. Shota Imanaga, two guys who can give up the long ball. So there's a lot going for a bunch of runs being scored.
The Padres don't typically help in that regard. They've scored 321 runs this year, the least in the league. But check out the splits:
- Padres at home: .217/.300/.354, 41 HR
- Padres on road: .226/.295/.379, 43 HR
Only slightly better in AVG/OBP on the road, but 25 more points in SLG. Imanaga has given up 14 homers to right-handed bats this year. Only three pitchers have given up a worse home run rate to righties this year. That plus the wind plus a few very competent right-handed sticks on the Padres side make it look pretty rough Shota.
But the books have priced it all in. An 11.5 total is wild. I'm not sure if that's a proper recommendation.
The way I've liked attacking these Wrigley spots is with team home runs. To take advantage of the wind, you've still gotta hit a ball pretty hard in the air. Both teams are in great shape to do that, but who is to say who is going to hit the dinger? And the home prices are all crazy in this one.
If you can find a good price on either team over 1.5 team homers, that's how I'd go about it.
Pick: Nothing specific, but go shopping for advantageous home run lines.
