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UFC 250 Picks & Betting Guide: Odds, Predictions, Promos for Nunes vs. Spencer

UFC 250 Picks & Betting Guide: Odds, Predictions, Promos for Nunes vs. Spencer article feature image

Jeff Bottari/Zuffa LLC. Pictured: Inside the UFC APEX.

  • Looking for betting and DFS advice before UFC 250 starts tonight (6 p.m. ET on ESPN/ESPN+)? Well you've come to the right place.
  • Tonight's card is headlined by double-champ Amanda Nunes (-625) who will face off against massive underdog Felicia Spencer (+450).
  • From betting previews to promos, we have everything you need below to get you ready for Saturday night's action.

The weekend is here, which means the action in the octagon will once again dominate the airwaves.

UFC 250, a 12-fight event headlined by the featherweight title fight between Amanda Nunes and Felicia Spencer, begins at 6 p.m. ET tonight at the UFC APEX in Las Vegas. The seven-fight undercard will air on ESPN/ESPN+ with the five-bout main card moving to ESPN PPV around 10 p.m. ET.

In anticipation of the action, we’ve got a wide menu of betting and DFS coverage for UFC 250.

UFC 250 PROMOS! Bet Amanda Nunes at +500 odds, boosted from -600!

UFC 250 Betting & DFS Previews

Projections for All 12 Fights

Whether you’re new to betting UFC or an expert it’s not easy finding an edge on every UFC fight on a given card. Sean Zerillo analyzes ever matchup using projections to make his picks for UFC 250.

UFC 250 DFS Breakdown

Using Sean Koerner’s DFS model featuring scoring projections for every fight on Saturday, we breakdown all the best potential plays to give you a leg up in DraftKings’ millionaire-maker contest. Check it out before locking in your lineups.

Aljamain Sterling vs. Cory Sandhagen Preview

With the winner of tonight’s Aljamain Sterling vs. Cory Sandhagen matchup likely to become the No. 1 contender in the division, here’s how we’re betting the much anticipated bout at UFC 250.

Raphael Assuncao vs. Cody Garbrandt Preview

Cody Garbrandt has been out of the octagon for more than a year. We analyzes his chances to snap his losing streak against Raphael Assuncao in tonight’s UFC 250 co-main event.

Amanda Nunes vs. Felicia Spencer Prop Bets

You may have heard, but Amanda Nunes (the UFC’s pound-for-pound top woman fighter) is a huge favorite to win here 11th-straight fight on Saturday against Felicia Spencer. With that in mind, Sean Zerillo looks at ways to bet Nunes and still get some value.

Staff Favorite Bets

With so many fights to choose from, our combat team of Sean Zerillo and Malik Smith each list their favorite bets for UFC 250’s main card.

The Early Bet to Lock in for UFC 250

With 12 fights on Saturday night’s UFC 250 card, there’s a good opportunity to find some value bets. But among the fights offering value, one stands out in particular for Sean Zerillo: Alex Caceres vs. Chase Hooper.

Best Promotions for UFC 250

In advance of Saturday’s action, sportsbooks have released some pretty exciting promos that center around the five fights on the main card, including the main event between Nunes and Spencer. Here, we’ve compiled a list of the top promos you can bet right now in your state.

UFC 250 Odds

Odds as of Friday June 5 and via DraftKings

Favorite Underdog
Herbert Burns (-230) Evan Dunham (+180)
Alonzo Menifield (-235) Devin Clark (+183)
Alex Perez (-137) Jussier Formiga (+111)
Charles Byrd (-180) Maki Pitolo (+143)
Cody Stamman (-275) Brian Kelleher (+210)
Ian Heinsich (-130) Gerald Meerschaert (+105)
Chase Hooper (-200) Alex Caceres (+162)
Sean O’Malley (-500) Eddie Wineland (+360)
Neil Magny (-136) Anthony Rocco Martin (+108)
Aljamain Sterling (-112) Cory Sandhagen (-112)
Cody Garbrandt (-148) Raphael Assuncao (+120)
Amanda Nunes (-625) Felicia Spencer (+450)

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