The college baseball regular season is over, the selection committee has made its picks, and we now have the 2025 NCAA Tournament bracket in front of us.
This is one of the best times of the year, and I have two picks, in particular, that I'm eyeing for Regionals.
With that said, let's dive into my college baseball picks and NCAA baseball predictions for the 2025 NCAA Regionals.
College Baseball Picks for NCAA Regionals
- Clemson +135 to Win Clemson Regional
- Oregon -175 to Win Eugene Regional

Clemson Tigers
+135 to Win Clemson Regional · DraftKings
Clemson is listed at +115, which is surprising because that shouldn't be the case. I have the Tigers closer to the -190/-210 range for all of their games in this Regional.
Their pitching, led by Aidan Knaack, is really what sets them apart.
West Virginia, meanwhile, isn't in a good spot. The Mountaineers haven't performed well in Big 12 play, so they shouldn't be much of a threat in this spot. They simply haven't faced a ton of tough competition, and the numbers they've put up against that competition aren't all that impressive.
Now, Clemson didn't have the best run in the ACC Tournament, making quite a few mistakes in the field while struggling with timely hitting. Georgia Tech and North Carolina are stronger teams in the ACC, but that doesn't have an impact on this Regional.
I'd make the Tigers closer to -290 to win this Regional instead of the current +135 out in the market, so I'd even take them all the way to -150.
Clemson has the experience and a solid coach in Erik Bakich, making the Tigers my clear pick here.

Oregon Ducks
-175 to Win Eugene Regional · DraftKings
Oregon's odds are also off in the market right now. The current line of -210 doesn't reflect how dominant the Ducks should be in Eugene, as I'd actually put them closer to -290.
I've crunched the numbers for the three games they're expected to play, coming up with odds of -170, -230 and -200.
Oregon's biggest threat will probably be Arizona, but the Wildcats have fallen apart as the season has wrapped up — so much so that they might not have even made the tournament if the regular season had lasted another couple of weeks.
Now, the Ducks would have an incredibly tough draw going to North Carolina for the Super Regionals. The Tar Heels can hang with any SEC team, so making the long coast-to-coast trip to Chapel Hill is less than ideal. However, they should at least make it to that point.
Oregon is a little juicy here, so it might be worth taking a flyer on a parlay with Clemson or another team in this spot.