The Duke Blue Devils host the Murray State Racers in the Durham Super Regional for the 2025 NCAA Baseball Tournament.
Duke enters as a -380 favorite to advance to the College World Series, while Murray State sits at +290.
Let's dive into our Duke vs. Murray State prediction and NCAA baseball picks for the Durham Super Regional.
Duke vs Murray State Prediction
- Game 1: Duke -2.5 (-130 · bet365)
- Game 2: Over 13.5 or Better
We have two best bets for the Durham Super Regional. Check out more college baseball content on our NCAA Baseball page.
Duke vs Murray State Odds
 | Duke Odds | -380 (Series) |
 | Murray State Odds | +290 (Series) |
Read Doug Ziefel's full college baseball betting preview for the 2025 NCAA Super Regionals here.
Projected Pitching Matchups for Durham Super Regional
- Game 1: Owen Proksch (DUKE) vs. Nic Schutte (MURR) · Saturday, June 7, 1 p.m. ET (ESPNU)
- Game 2: Andrew Healy (DUKE) vs. Isaac Silva (MURR) · Sunday, June 8, 12 p.m. ET (ESPN2)
- Game 3 ( If necessary): Henry Zatkowski (DUKE) vs. Kane Elmy (MURR) · Monday, June 9
The potential for this Duke team was always there on paper. Its lineup is amongst the most dangerous in the country, ranking fifth in wRC+ and 15th in OPS.
The Blue Devils picked the right time to figure things out on the mound, holding Georgia to three runs and Oklahoma State to just seven runs over two games.
They’ll need a repeat performance as they host the Murray State Racers.
The Racers just never quit in the Oxford Regional and outslugged two potent lineups in Ole Miss and Georgia Tech.
While Murray State is a dangerous offensive team in its own right, its pitching doesn't project for continued success. The Racers' staff ERA over their last 10 games came in at 7.07, and while their xFIP is 5.61, that type of pitching isn't going to work against a lineup like Duke’s.
The Blue Devils' pitching staff is due for positive regression, and we’ve started to see it against lineups tougher than the Racers'.
Murray State has been a nice story, but with Duke rounding into form, we should expect its run to end in disappointing fashion.
Duke vs Murray State Pick, Best Bets
- Game 1: Duke -2.5 (-130 · bet365)
- Game 2: Over 13.5 or Better
