Louisville vs. Cincinnati Odds & Betting Predictions - November 21, 2025
Louisville at Cincinnati
11:30 pm • ESPN2Louisville at Cincinnati Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Louisville 20-9 | -8.5-110 | o163.5-110 | -470 | |
 Cincinnati 16-13 | +8.5-110 | u163.5-115 | +355 | |
Fifth Third ArenaCincinnati
Louisville vs. Cincinnati Expert Picks
Cam Is Money
Last 30d: 47-44-0 (-0.5u)
LOU -125 (Live)
0.8u
CTO
Last 30d: 25-20-0 (+27.1u)
CIN +5.5 (1H)-110
1.82u
Ryan Minion
Last 30d: 159-188-0 (+65.4u)
M.Brown o15.5 Pts-120
$1.00
Babs .
Last 30d: 31-27-0 (+2.2u)
Under 164.5-115
0.87u
Ryan Minion
Last 30d: 159-188-0 (+65.4u)
LOU -8.5-110
$1.00
LOU -4.5 (1H)-110
$1.10
Will Brinson
Last 30d: 1-14-0 (-5.5u)
LOU -8.5-111
1u
Sean Paul
Last 30d: 38-48-0 (-13.1u)
CIN +8.5-110
1u
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Louisville vs. Cincinnati Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Cincinnati Public Betting Percentages
Betting Trends
- Cincinnati are 4-1 in their last 5 games.
- Cincinnati are 3-2 in their last 5 games against the spread
- Cincinnati are 4-7 in their road games against the spread
- The totals have gone OVER in 4 of Cincinnati' last 5 games
- The totals have gone OVER in 5 of Cincinnati' 18 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 13-16 | 9-9 | 4-7 | 9-7 | 4-8 |
| 13-16 | 8-8 | 5-8 | 10-11 | 0-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 10-18-1 | 5-12-1 | 5-6 | 5-10-1 | 4-8 |
| 11-18 | 5-11 | 6-7 | 9-12 | 0-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 16-13 | N/A | N/A | 13-3 | 2-10 |
| 20-9 | N/A | N/A | 15-6 | 0-3 |
Last 5 Matchups
Cincinnati vs. Louisville Injury Updates
Cincinnati Injuries
- Jalen HaynesF
Haynes is out for season with lower body
Out for Season
- Tyler McKinleyF
McKinley is questionable with undisclosed
Questionable
- Jordi RodriguezG
Rodriguez is questionable with undisclosed
Questionable
Louisville Injuries
- Mikel BrownG
Brown is out with undisclosed
Out
Team Stats
21-56 (38%)
Field Goals
23-62 (37%)
24-28 (86%)
Free Throws
10-16 (63%)
8-28 (29%)
3P
8-29 (28%)
35
Rebounds
35
13
Assists
19
13
Turnovers
13
9
Steals
5
4
Blocks
7
23
Fouls
19
Louisville vs. Cincinnati Odds Comparison
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Louisville at Cincinnati Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 20-9 | N/A | N/A |
Cincinnati 16-13 | N/A | N/A |