Michigan St vs. Iowa Odds & Betting Predictions - November 22, 2025
Michigan St at Iowa
8:30 pm • Fox Sports 1Michigan St at Iowa Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Michigan St 2-6 | +17.5 | +17.5-115 | o42.5-111 | +587 |
Iowa 5-2 | u43.5 | -17.5-106 | u42.5-110 | -900 |

Kinnick StadiumIowa City
Michigan St vs. Iowa Expert Picks

Sean Zerillo
Last 30d: 142-131-7 (+3.6u)
MSU +17.5-115
0.25u
Jeremiah Rose
Last 30d: 53-61-3 (-2.1u)
IOWA -16-120
0.5u
Boomer’s Book
Dan Gaspar
Last 30d: 32-26-3 (+3.2u)
N.Marsh o35.5 Rec Yds-115
1.15u
K.Moulton o6.5 Rec Yds-115
1u
Greg Matherne
Last 30d: 22-25-1 (-3.9u)
MSU +17-109
0.5u
Babs .
Last 30d: 42-34-2 (+1.5u)
MSU +17-113
0.88u
Michigan St vs. Iowa Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Michigan St vs. Iowa Public Betting Percentages
Betting Trends
- Iowa are 3-2 in their last 5 games.
- Iowa are 2-3 in their last 5 games against the spread
- Iowa are 2-1 in their road games against the spread
- The totals have gone OVER in 0 of Iowa' last 5 games
- The totals have gone OVER in 1 of Iowa' 4 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 4-3 | 2-2 | 2-1 | 1-2 | 2-1 | |
| 4-4 | 3-2 | 1-2 | 1-1 | 3-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 2-5 | 1-3 | 1-2 | 0-3 | 1-2 | |
| 2-6 | 2-3 | 0-3 | 1-1 | 1-5 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-2 | N/A | N/A | 2-1 | 2-1 | |
| 2-6 | N/A | N/A | 2-0 | 0-6 |
Last 5 Matchups
Team Stats
335
Total Yards
301
69
Total Plays
61
4.855072463768116
Yards Per Play
4.934426229508197
255
YDS
147
25/42
Comps/Atts
12/22
6.071428571428571
YPA
6.681818181818182
2/1
TDs/INTs
1/1
2/17
Sacks/Yards
3/8
1/10
Penalties/Yards
4/40
Michigan St vs. Iowa Odds Comparison
Could not load odds
Michigan St at Iowa Team Totals
MatchupOverUnder | ||
|---|---|---|
Michigan St 2-6 | N/A | N/A |
Iowa 5-2 | N/A | N/A |




