Michigan St vs. Iowa Odds & Betting Predictions - November 22, 2025

Michigan St at Iowa

8:30 pm • Fox Sports 1

Michigan State Spartans

@

Iowa Hawkeyes

MatchupOpenSpreadTotalMoneyline
Michigan St 3-7	+15.5	+16.5-109	o43-112	+600
Iowa 6-4	u43.5	-16.5-111	u43-110	-900

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Saturday 8:30 p.m.

November 22, 2025

Kinnick StadiumIowa City

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46°Fahrenheit

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0%Rain

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9Wind

No props found

NCAAF Public Betting

Iowa are 3-2 in their last 5 games.
Iowa are 3-2 in their last 5 games against the spread
Iowa are 4-0 in their road games against the spread
The totals have gone OVER in 2 of Iowa' last 5 games
The totals have gone OVER in 3 of Iowa' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Iowa	8-2	4-2	4-0	3-2	4-0
Michigan St	5-5	1-5	4-0	0-4	5-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Iowa	4-6	3-3	1-3	3-2	0-4
Michigan St	6-4	3-3	3-1	2-2	4-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Iowa	6-4	N/A	N/A	5-0	0-4
Michigan St	3-7	N/A	N/A	3-1	0-6

date	opponent	score	spread	over/under	moneyline
Nov 15th	@USC	L 21-26	+6.5 W	U 48.5	USC +192
Nov 8th	ORE	L 16-18	+4.5 W	U 41.5	ORE +170
Oct 25th	MINN	W 41-3	-7.5 W	O 39.5	IOWA -300
Oct 18th	PSU	W 25-24	-3.5 L	O 41.5	IOWA -162
Oct 11th	@WIS	W 37-0	-5.5 W	U 37.5	IOWA -230

Total

Passing

2125

YDS

1336

188/297

Comps/Atts

143/226

7.15

YPA

5.91

14/4

TDs/INTs

8/6

35/288

Sacks/Yards

13/74

Rushing

1233

Rush Yards

1766

332

Attempts

382

3.71

YPC

4.62

16

TDs

22

Turnovers

Fumbles Lost

4

Interceptions

6

Efficiency

31/35 88.6%

Redzone

37/40 92.5%

46/130 0%

3rd Down

56/127 0%

11/25 0%

4th Down

11/16 0%

First Downs

183

Total

174

88

Pass

68

72

Rush

95

23

Penalty

11

Misc

/

Penalties/Yards

/

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See more NCAAF Odds

MatchupOverUnder
Michigan St 3-7	N/A	N/A
Iowa 6-4	N/A	N/A