Notre Dame vs. Purdue Odds & Betting Predictions - September 26, 2026

Notre Dame at Purdue

6:00 pm • Peacock
49 - 10

Notre Dame at Purdue Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Notre Dame
7-1
-27.5
-27.5-110
o56.5-115
-5000
Purdue
3-5
u56.5
+27.5-110
u56.5-108
+1700
location pinSaturday 6:00 p.m.
September 26, 2026
Ross-Ade StadiumWest Lafayette
Notre Dame vs. Purdue Expert Picks
Collin Wilson
Collin Wilson
Last 30d: 86-59-2 (+13.0u)
Over 56.5-115
1u
Project 61.5; Purdue offense 2nd quality drives and T10 passing success rate. Notre Dame bottom 5 nationally in pass rush. Irish should have no issues w explosives rush or pass v Purdue D
Mike McNamara
Mike McNamara
Last 30d: 80-57-1 (+10.4u)
ND -27.5-110
0.27u
Doug Ziefel
Doug Ziefel
Last 30d: 411-345-10 (+42.8u)
Over 57.5-110
0.5u
Ryan Minion
Ryan Minion
Last 30d: 237-257-8 (-7.7u)
ND o41.5-125
$2.00
ND -27.5-110
$1.00
#ACTION ✍️✍️ https://discord.gg/cP6X2bgkS
Topper
Topper
Last 30d: 115-105-2 (-22.7u)
ND -27.5-108
0.93u
The Right Favorite Overall: 742-558-22,57% (ROI:10%) Season:1-4-0,20% (ROI:-62%) #TSA

Notre Dame vs. Purdue Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Notre Dame vs. Purdue Public Betting Percentages

Away Logo

Notre Dame

Public

49%

Bets%

51%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Purdue
3-52-31-20-23-3
Notre Dame
4-42-11-22-4N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Purdue
6-25-01-22-04-2
Notre Dame
5-31-23-04-2N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Purdue
3-5N/AN/A1-12-4
Notre Dame
7-1N/AN/A5-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 20th@UCLAL 38-52+13.5 LO 53.5UCLA +450
Sep 12thWFL 36-38+2.5 WO 51.5WF +120
Sep 4thINSTW 44-19-35.5 LO 56.5-
Nov 29thIUL 3-56+28.5 LO 54.5IU +1800
Nov 16th@WASHL 13-49+14.5 LO 50.5WASH +524
Team Stats
444
Total Yards
218
58
Total Plays
68
7.655172413793103
Yards Per Play
3.2058823529411766
267
YDS
178
16/26
Comps/Atts
25/37
10.26923076923077
YPA
4.8108108108108105
4/1
TDs/INTs
1/0
0/0
Sacks/Yards
6/46
177
Rush Yards
40
32
Attempts
31
5.53125
YPC
1.2903225806451613
2
TDs
0
0
Fumbles Lost
1
1
Interceptions
0
4/4 100%
Redzone
1/2 50%
3/8 0%
3rd Down
8/18 0%
1/1 0%
4th Down
0/2 0%

First Downs

19
Total
16
10
Pass
7
8
Rush
8
1
Penalty
1
1/15
Penalties/Yards
6/46

Notre Dame vs. Purdue Odds Comparison

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Notre Dame at Purdue Team Totals

MatchupOverUnder
Notre Dame
7-1
N/A
N/A
Purdue
3-5
N/A
N/A