Southern Miss vs. Louisiana Odds & Betting Predictions - October 18, 2025
Southern Miss at Louisiana
9:00 pm • ESPN+Southern Miss at Louisiana Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Southern Miss 1-5 | -2.5 | -5-110 | o54.5-110 | -196 |
Louisiana 5-2 | u54.5 | +5-110 | u54.5-115 | +165 |

Cajun Field at Our Lady of Lourdes StadiumLafayette
Southern Miss vs. Louisiana Expert Picks
Greg Matherne
Last 30d: 21-27-1 (-5.5u)
Under 54.5-105
0.5u
Southern Miss vs. Louisiana Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Southern Miss vs. Louisiana Public Betting Percentages
Betting Trends
- Louisiana are 4-1 in their last 5 games.
- Louisiana are 4-1 in their last 5 games against the spread
- Louisiana are 3-0 in their road games against the spread
- The totals have gone OVER in 1 of Louisiana' last 5 games
- The totals have gone OVER in 0 of Louisiana' 4 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-1-1 | 2-1-1 | 3-0 | 3-1-1 | 2-0 | |
| 2-4 | 1-2 | 1-2 | 1-0 | 1-4 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 2-5 | 0-4 | 2-1 | 0-5 | 2-0 | |
| 3-3 | 2-1 | 1-2 | 1-0 | 2-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-2 | N/A | N/A | 5-0 | 0-2 | |
| 1-5 | N/A | N/A | 1-0 | 0-5 |
Last 5 Matchups
Team Stats
363
Total Yards
356
58
Total Plays
75
6.258620689655173
Yards Per Play
4.746666666666667
230
YDS
135
12/17
Comps/Atts
14/27
13.529411764705882
YPA
5
1/1
TDs/INTs
0/2
0/0
Sacks/Yards
2/11
133
Rush Yards
221
41
Attempts
48
3.2439024390243905
YPC
4.604166666666667
1
TDs
1
6/43
Penalties/Yards
8/70
Southern Miss vs. Louisiana Odds Comparison
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Southern Miss at Louisiana Team Totals
MatchupOverUnder | ||
|---|---|---|
Southern Miss 1-5 | N/A | N/A |
Louisiana 5-2 | N/A | N/A |




