The Troy Trojans take on the Missouri Tigers in Columbia, Missouri. Kickoff is set for 7:00 p.m. EDT on SEC Network+.
Missouri is favored by 26.5 points on the spread with a moneyline of -4500. The total is set at 50.5 points.
Here’s my Troy vs. Missouri prediction and college football pick for Saturday, September 19, 2026.
Troy vs Missouri Prediction
- Troy vs. Missouri Pick: Over 51 or Better
My Missouri vs. Troy best bet is on the Over. Find the best line available on our live NCAAF odds page.
Troy vs Missouri Odds
| Troy Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+26.5 -110 | 50.5 -106o / -114u | +1600 |
| Missouri Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-26.5 -110 | 50.5 -106o / -114u | -4500 |
- Troy vs Missouri point spread: Missouri -26.5 (-110), Troy +26.5 (-110)
- Troy vs Missouri over/under: 50.5 (-106o / -114u)
- Troy vs Missouri moneyline: Troy +1600, Missouri -4500
Troy vs Missouri College Football Preview
This game triggered one of our Action PRO betting systems, powered by Evan Abrams:
In both regular season and postseason college football, large home favorites in non-conference matchups often create conditions for higher scoring than the market anticipates.
When the point spread is wide, but the total is set low, it signals expectations of a dominant performance by one side while undervaluing their ability to score quickly and consistently.
Non-conference games can feature mismatches in talent and depth, leading to offensive surges and late scoring from backups against overmatched defenses.
This combination often pushes the total over despite conservative pregame projections.
Pick: Over 51 or Better
