The San Francisco 49ers and Los Angeles Rams meet in Australia for the first edition of Thursday Night Football for the 2026-27 NFL season. Kickoff is scheduled for 8:35 p.m. ET at Melbourne Cricket Ground; the game can be streamed on Netflix.
For my 49ers vs Rams anytime touchdown picks, I'm targeting one player from each side: Davante Adams and Deebo Samuel.
Continue below for my 49ers vs Rams anytime touchdown preview for Thursday Night Football Week 1.
49ers vs Rams Anytime Touchdown Props
- Davante Adams Anytime Touchdown (+140; DraftKings)
- Deebo Samuel Anytime Touchdown (+350; FanDuel)
49ers vs Rams Anytime Touchdown Scorer Picks
Davante Adams Anytime Touchdown (+140)
Adams tallied 14 touchdowns in 14 games in his debut season with the Rams — he was an absolute in the menace in the red zone and led all pass-catchers with 23 targets inside the 10-yard line, where 11 of Adams' TDs were scored.
Last season against the 49ers, Adams was never plus-money to score in those two games so I'm jumping all over this price of +140 at the time of writing.
With his all-world ability to beat man coverage, I fully expect Adams to get another TD in Week 1.
Pick: Davante Adams Anytime Touchdown Scorer
Deebo Samuel Anytime Touchdown (+350)
Samuel scored six touchdowns (five receiving, one rushing) last season with the Commanders. He also led the team in snaps played and was a reliable presence all season.
He may be counted on more to start the year given the uncertainty surrounding the 49ers' pass-catchers. Ricky Pearsall is out, Mike Evans is dealing with injuries, rookie De'Zhaun Stribling is unproven and veteran George Kittle is coming off an Achilles injury.
Samuel's versatility as a receiver and a runner makes this +350 line a bit too steep. This is the healthiest he's going to be all season and also just a great matchup for him.
Pick: Deebo Samuel Anytime Touchdown Scorer
