Cardinals vs Saints Predictions, Parlay, Picks, Odds for NFL Week 1 article feature image
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Cardinals vs Saints Predictions, Parlay, Picks, Odds for NFL Week 1

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Imagn/Action Network. Pictured: Kyler Murray, Spencer Rattler.

The Arizona Cardinals (0-0) and New Orleans Saints (0-0) will face off in NFL Week 1. Kickoff is set for in 1:00 p.m. EDT from Caesars Superdome in New Orleans, La. The game will broadcast live on CBS.

The Cardinals are favored by -6.5 with the over/under set at 43 total points. The Cardinals are -300 moneyline favorites to win outright and the Saints are +240 to pull off the upset.

Let's get into my Cardinals vs. Saints predictions and parlay for Sunday afternoon.

Quickslip

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Cardinals vs Saints Predictions, Parlay

  • Cardinals Moneyline (-285)
  • Chris Olave 60+ Receiving Yards (+123)

Parlay Odds: +195 (Fanatics)


Cardinals vs Saints Odds

Cardinals Logo
Sunday, Sep 7
1 p.m. ET
CBS
Saints Logo
Cardinals Odds
SpreadTotalMoneyline
-6.5
-110
43
-110o / -110u
-300
Saints Odds
SpreadTotalMoneyline
+6.5
-110
43
-110o / -110u
+240
Odds via BetMGM. Get up-to-the-minute NFL odds here.
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Cardinals vs Saints NFL Week 1 Preview, Parlay

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Cardinals Moneyline

New Orleans will be one of the worst teams in football this season, mainly due to their below-average offense. Meanwhile, I am optimistic about this Cardinals; I think Kyler Murray will have the Cardinals' offense ready to go, and I expect Arizona to control the pace of this game.

It's hard to see a path to victory here for the Saints, who are starting Spencer Rattler at quarterback

New Orleans will struggle to keep pace this afternoon.


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Chris Olave 60+ Receiving Yards

Olave had a quiet 2024 season due to injuries. The former Ohio State standout was limited to just eight games with 32 receptions, 400 yards and a touchdown. It was the first time he didn't surpass 1,000 receiving yards in his NFL career.

But Olave appears to be fully healthy heading into the season, which is a scary sight for the rest of the league. Beyond Olave, there' not much else the Saints have going on besides Alvin Kamara.

The Cardinals enter this game as 5.5-point favorites on the spread, so the potential trailing game script bodes well for Olave, who is one of the few quality pieces on the Saints offense.


Cardinals vs Saints Parlay

  • Cardinals Moneyline
  • Chris Olave 60+ Receiving Yards

Parlay Odds: +195 (Fanatics)


Cardinals vs Saints Betting Trends


Cardinals vs Saints Weather

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About the Author
Matt is a Senior Betting Analyst at Action Network. He has been in the betting industry for eight years and has worked as a Lead Betting Analyst for numerous companies over the years. Matt specializes in multiple sports, including NFL, NBA, MLB, NHL, NCAAF, NCAAB, UFC, Golf and NASCAR.

Follow Dead President Picks @DeadPresPicks on Twitter/X.

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