Thursday Night Football for NFL Week 4 will spotlight the Arizona Cardinals and Seattle Seahawks at State Farm Stadium (8:15 p.m. ET), and will be broadcast on Amazon Prime Video.
Below, you can find Thursday Night Football odds and my Cardinals vs Seahawks parlay — which includes a moneyline pick and a Kyler Murray passing yards prop.
- Seattle Seahawks ML
- Kyler Murray 175+ Passing Yards
Parlay Odds: +135 (bet365)
Cardinals vs Seahawks Odds
Seahawks Odds | ||
---|---|---|
Spread | Total | Moneyline |
-1.5 -105 | 43.5 -110o / -110u | -120 |
Cardinals Odds | ||
---|---|---|
Spread | Total | Moneyline |
+1.5 -115 | 43.5 -110o / -110u | +100 |
- Cardinals vs Seahawks Moneyline: Cardinals +100, Seahawks -120
- Cardinals vs Seahawks Total: 43.5
- Cardinals vs Seahawks Spread: Cardinals +1.5 (-115), Seahawks -1.5 (-105)
Cardinals vs Seahawks Preview, Parlay Picks

Seahawks Moneyline
The Seahawks enter this contest coming off a dominant 44-13 win over the Saints on Sunday.
I have been impressed early in the season with quarterback Sam Darnold and this Seattle offense. The Seahawks rank fifth in points per game early in the season (29.3), fifth in Overall Offensive DVOA (per FTN).
Arizona, meanwhile, has struggled on the offensive side of the football, ranking 19th in points per game (20.7).
Things will only get more difficult for the Cardinals on offense as they will be without star running back James Conner. He is a key piece on a team that is thin at the running back position.
I expect Arizona to become more one-dimensional in the absence of Conner and struggle to keep pace in this game.

Kyler Murray 175+ Passing Yards
QB Kyler Murray will be in a strong game script to cash this prop.
I expect Arizona to play the majority of this game from behind, which could mean more passing opportunities for the former Oklahoma standout. The loss of Conner to injury could also impact how much Murray throws in this game.
Murray should earn 30+ passing attempts, which will bode well for this prop.
Last season, he went over 175 yards in both games against the Seahawks.
Cardinals vs Seahawks Parlay
- Seattle Seahawks ML
- Kyler Murray 175+ Passing Yards
Parlay Odds: +135 (bet365)