The Los Angeles Rams (9-2) and Carolina Panthers (6-6) will face off in NFL Week 13. Kickoff is set for 1:00 p.m. ET from Bank of America Stadium in Charlotte, N.C. The game will broadcast live on FOX.
The Rams are 10.5-point favorites over the Panthers on the spread (Rams -10.5), with the over/under set at 44.5. Los Angeles is a -550 favorite to win outright on the moneyline, while Carolina is +400 to pull off the upset.
Let's get into my Rams vs Panthers prediction today's Week 13 contest.
- Rams vs Panthers pick: Over 44.5 (-110)
My Rams vs Panthers best bet is on the over. Find the best odds by checking our live NFL odds page.
Rams vs Panthers Odds
| Rams Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-10.5 -110 | 44.5 -110o / -110u | -550 |
| Panthers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+10.5 -110 | 44.5 -110o / -110u | +400 |
Rams vs Panthers Week 13 Preview
Do I worry about the Panthers' offense? Yeah, you never really know what you’re going to get.
However, Bryce Young — who's prone to dud performances — has historically been better at home, so I'm comfortable taking the over here.
The bigger question is how this Panthers defense is going to get stops against the Rams. The Panthers are absolutely decimated at corner and linebacker right now.
The Panthers also can’t generate pressure, which is a major problem against the Rams, who always travel well, especially to the East Coast under Sean McVay.
Carolina is likely going to be forced to throw a ton due to game script, and the Rams' secondary is still somewhat vulnerable; they’ve faced a backup quarterback almost every other week, which has inflated their numbers.
The Rams defense is strong because of the front, and they were shutting down Baker Mayfield, although the Bucs offense has been broken for about a month. To their credit, the Rams did a lot of damage in that first half of that game.
The Panthers were already down their top two linebackers, and then the next one got hurt. Jaycee Horn had a concussion and was throwing up. Another corner went down. It just kept happening. They were moving guys all over the field.
Carolina's defense isn't very deep. We saw what happened to the Panthers last year when the injuries piled up; it gets dark quickly.
Rams vs Panthers Prediction, Betting Analysis
I think the Panthers can contribute enough offensively to send this game over the number, and this total feels a bit low considering all the defensive injuries on Carolina’s side.
With Matthew Stafford and the Rams offense likely controlling the script and the Panthers forced to throw, there should be plenty of opportunities for points.
Given how depleted Carolina’s defense is (No Jaycee Horn, Christian Rozeboom, Claudin Cherelus) and how vulnerable the Rams' secondary can be, this number is slightly too low.
Pick: Over 44.5 (-110)
Spread
I'm not betting either side of the spread in this contest.
Moneyline
I have no bet on the moneyline as well.
Over/Under
My Panthers vs Rams prediction is on the over at 44.5 total points.



















