Week 10 NFL Odds: Spreads, Totals & Opening Lines For Every Game

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Will Newton/Getty Images. Pictured: Lamar Jackson vs. the Patriots in 2019.

Patriots-Jets on Monday Night Football is the only matchup remaining on the Week 9 schedule, but oddsmakers have already released Week 10 opening lines.

We’ve outlined all the posted spreads and totals available as of Sunday night below.

Week 10 NFL Odds: Spreads & Totals


Odds as of Sunday night and via FanDuel. Get up to a $1,000 risk-free bet at FanDuel today or see more offers and reviews for the best online sportsbooks.


Colts at Titans

  • Odds: Titans -2.5 [BET NOW]
  • Over/Under: 50 [BET NOW]
  • Time: 8:20 p.m. ET on Nov. 12
  • TV Channel: FOX, NFL Network

Texans at Browns

  • Odds: Browns -3 [BET NOW]
  • Over/Under: 54.5 [BET NOW]
  • Time: 1 p.m. ET on Nov. 15
  • TV Channel: FOX

Washington at Lions

  • Odds: TBD
  • Over/Under: TBD
  • Time: 1 p.m. ET on Nov. 15
  • TV Channel: FOX

Buccaneers at Panthers

  • Odds: TBD
  • Over/Under: TBD
  • Time: 1 p.m. ET on Nov. 15
  • TV Channel: FOX

Eagles at Giants

  • Odds: Eagles -3.5 [BET NOW]
  • Over/Under: 41.5 [BET NOW]
  • Time: 1 p.m. ET on Nov. 15
  • TV Channel: FOX

Jaguars at Packers

  • Odds: Packers -14 [BET NOW]
  • Over/Under: 53.5 [BET NOW]
  • Time: 1 p.m. ET on Nov. 15
  • TV Channel: FOX

Bills at Cardinals

  • Odds: Cardinals -1.5 [BET NOW]
  • Over/Under: 53.5 [BET NOW]
  • Time: 4:05 p.m. ET on Nov. 15
  • TV Channel: CBS

Chargers at Dolphins

  • Odds: Dolphins -2.5 [BET NOW]
  • Over/Under: 49.5 [BET NOW]
  • Time: 4:05 p.m. ET on Nov. 15
  • TV Channel: CBS

Broncos at Raiders

  • Odds: Raiders -4.5 [BET NOW]
  • Over/Under: 51 [BET NOW]
  • Time: 4:05 p.m. ET on Nov. 15
  • TV Channel: CBS

Seahawks at Rams

  • Odds: Rams -1.5 [BET NOW]
  • Over/Under: 55.5 [BET NOW]
  • Time: 4:25 p.m. ET on Nov. 15
  • TV Channel: FOX

Bengals at Steelers

  • Odds: Steelers -9.5 [BET NOW]
  • Over/Under: 48.5 [BET NOW]
  • Time: 4:25 p.m. ET on Nov. 8
  • TV Channel: FOX

49ers at Saints

  • Odds: TBD
  • Over/Under: TBD
  • Time: 4:25 p.m. ET on Nov. 8
  • TV Channel: FOX

Ravens at Patriots

  • Odds: Ravens -6.5 [BET NOW]
  • Over/Under: 41 [BET NOW]
  • Time: 8:20 p.m. ET on Nov. 15
  • TV Channel: NBC

Vikings at Bears

  • Odds: Bears -1 [BET NOW]
  • Over/Under: 44.5 [BET NOW]
  • Time: 8:15 p.m. ET on Nov. 16
  • TV Channel: ESPN
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