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Steelers vs Patriots Predictions, Odds, NFL Picks

Steelers vs Patriots Predictions, Odds, NFL Picks article feature image
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Reuters Connect/Imagn. Pictured: Aaron Rodgers, Drake Maye.

The Pittsburgh Steelers (1-0) and New England Patriots (0-1) clash in NFL Week 2 today. Kickoff is set for 1 p.m. ET from Gillette Stadium in Foxborough, Mass. The game will broadcast live on CBS.

Steelers vs Patriots odds list the Patriots as 5.5-point favorites on the spread. The over/under is 41.5. The Patriots are -235 favorites on the moneyline and the Steelers are +192 underdogs.

Let's get into my Steelers vs Patriots predictions and picks for Week 2.


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Steelers vs Patriots Prediction, Pick

  • Steelers vs Patriots pick: Patriots -5 (-110)

My Steelers vs Patriots best bet is on New England to cover the spread, with the best price currently available at FanDuel. Make sure to find the best odds by checking our live NFL odds page.

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Steelers vs Patriots Odds

Steelers Logo
Sunday, Sep 20
1 p.m. ET
CBS
Patriots Logo
Steelers Odds
SpreadTotalMoneyline
+5.5
-115
41.5
-110o / -110u
+194
Patriots Odds
SpreadTotalMoneyline
-5.5
-105
41.5
-110o / -110u
-235
Odds via FanDuel. Get up-to-the-minute NFL odds here.
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Steelers vs Patriots Preview

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Steelers

While the Patriots offense delivering a better performance takes some projection, the inefficiencies of the Steelers offense have plenty of numbers to use as evidence they are in for a long day at the office.

Pittsburgh rushed for a league-low 2.7 yards per carry and its 31% offensive success rate on all offensive plays was only better than one other NFL team in Week 1.

In addition to a non-existent rushing attack, Aaron Rodgers averaged just 5.5 yards per attempt. The Steelers' -0.4 EPA/pass ranked 27th in the NFL in Week 1.

It is quite clear head coach Mike McCarthy wants to push the ball down field more this season than did Rodgers a year ago, but Rodgers failed to complete a pass traveling 20+ yards past the line of scrimmage on his six attempts.

Rodgers' connection with DK Metcalf was lacking as well — the two connected on just four of his 10 targets. Metcalf lined up on the outside of the formation at an 86% rate, which means he will be an easy find to be shadowed by star cornerback Christian Gonzalez.

The Pittsburgh defense was not challenged as it was fortunate to play against Cooper Rush and the Falcons. However, there were some concerning advanced defensive metrics that are worth noting.

The Steelers generated pressure on just 30% of Rush’s dropbacks, which ranked 22nd. Pittsburgh opted to use a light box on 48% of defensive snaps and ranked 31st a week ago in allowing yards after contact on a per-attempt basis when defending the run.

I wasn’t convinced the Steelers boasted a top-10 defense heading into the season, and despite them allowing just 13 points to the Falcons, the same questions still remain.

The Steelers' defensive line is aging and they do not have reliable depth pieces behind Cam Heyward. Even if Joey Porter Jr. returns to the lineup, it will not affect my handicap of this game given the amount of time Patriots offensive coordinator Josh McDaniels had to prepare knowing he would not have the services of A.J. Brown.


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Patriots

For the second consecutive season, the Patriots played poorly in Week 1 and will be looking to bounce back.

With ample time to prepare for their home game against the Steelers and historical evidence suggesting the Patriots are a good bet to rebound, my confidence level is quite high that they can cover this modest number.

In the 2025 regular season, New England only had three losses but it followed those games up by going 3-0 against the number. On two of those occasions, the Patriots were road underdogs and won outright, and in the third they were victorious 42-13 as a 5.5-point favorite.

Drake Maye played very efficiently in those outings, completing 76.2% of his passes with a 124.8 passer rating in total.


Steelers vs Patriots Against the Spread Prediction

The return of TreVeyon Henderson should give the Patriots another explosive element on offense as they look to right the ship without A.J. Brown.

The Steelers defense is not on the same level as the Seahawks defense and they do not have the likes of Mike MacDonald calling plays.

Bettors undoubtedly have a bad taste in their mouths when it comes to Drake Maye after seeing him struggle against some of the league’s top pass rushes dating back to last year’s AFC Championship Game.

This line is starting to become more expensive at the -4.5 range, which makes playing anything under the key number of 6 the better option — you should be able to find -5 at -110 or better. That is the position I will be taking as I expect New England to make a statement on Sunday.

Pick: Patriots -5 (-110)


Steelers vs Patriots Trends


Steelers vs Patriots Viewing Info: Channel, Start Time, Streaming

Location:Gillette Stadium
Date:Sunday, Sept. 20
Time:1 p.m. ET
TV / Streaming Options:CBS

Steelers vs Patriots Inactives

Steelers Inactives

WR Michael Pittman Jr.
QB Drew Allar
QB Will Howard (Emergency 3rd QB)
CB Joey Porter Jr.
G Gennings Dunker
DL Kevin Jobity Jr.
DE Gabriel Rubio

Patriots Inactives

No. 7 CB Carlton Davis
No. 15 QB Behren Morton (Emergency 3rd QB)
No. 68 T Dametrious Crownover
No. 72 T Walter Rouse
No. 84 TE Tanner Arkin
No. 93 DT Leonard Taylor

Inactives via Steelers.com


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Author Profile
About the Author

John Lanfranca is a contributor at Action Network who specializes in NFL betting, with a focus on sides, totals, and player props. He has been betting since 2006 John has been involved with football since a young age and currently coaches at the high school level. He has cashed multiple five-figure entries in NFL DFS, which coincided with him entering the industry with Fantasysharks, where he contributed as a podcaster while also writing daily articles on betting, DFS, and the NFL Draft. John has shown a consistent ability to win when betting the NFL against the spread, regularly finishing seasons with a winning percentage in the 55-60% range

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