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Red Wings vs. Sabres Odds & Betting Predictions - October 22, 2025

Red Wings at Sabres

11:30 pm • TNT

Detroit Red Wings

15-11-3
2
2 - 4

Buffalo Sabres

11-13-4
4

Red Wings at Sabres Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Red Wings
15-11-3
+1.5
+1.5-247
o6.5+105
-102
Sabres
11-13-4
u6.5
-1.5+195
u6.5-125
-122
location pinWednesday 11:30 p.m.
October 22, 2025
KeyBank CenterBuffalo
Red Wings vs. Sabres Expert Picks
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 9-10-0 (-1.0u)
BUF +120 (Live)
0.6u
To Win in Regulation (No Overtime)
Bet Labs
Bet Labs
Last 30d: 25-18-0 (+5.6u)
Under 6.5-132
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 124-150-11 (-6.6u)
BUF -110
0.91u
The Degenerates
The Degenerates
Last 30d: 101-90-5 (+4.9u)
DET -110
1.1u
Picks Office
Picks Office
Last 30d: 223-167-4 (+36.7u)
DET +100
1u
X: PicksOffice
Scott Rickenbach
Scott Rickenbach
Last 30d: 104-107-0 (-14.4u)
BUF -110
0.91u
Nick Martin
Nick Martin
Last 30d: 71-114-1 (-12.2u)
T.Thompson Anytime Goal Scorer Yes+145
0.5u
https://www.dailyfaceoff.com/news/nhl-player-prop-bets-oct22
Allan Lem
Allan Lem
Last 30d: 163-128-3 (+7.3u)
B.Byram o0.5 Pts+185
0.26u
Tailing the ScoresAndOdds team
Lines at Lunch
Lines at Lunch
Last 30d: 29-37-5 (-11.9u)
BUF -104
1u

Red Wings vs. Sabres Previews & Analysis

  • Red Wings vs Sabres: A Moneyline Pick for Tonight article feature image

    Red Wings vs Sabres: A Moneyline Pick for Tonight

    Greg Liodice•
    Oct 22, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Red Wings vs. Sabres Public Betting Percentages

Away Logo

Red Wings

Public

Home Logo

Sabres

61%

Bets%

39%

Money%

NHL Public Betting Right Arrow

Betting Trends

  • Sabres are 3-2 in their last 5 games.
  • Sabres are 3-2 in their last 5 games against the spread
  • Sabres are 3-9 in their road games against the spread
  • The totals have gone OVER in 2 of Sabres' last 5 games
  • The totals have gone OVER in 6 of Sabres' 16 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Sabres		12-169-73-93-79-9
Red Wings		14-157-97-62-1111-4

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Sabres		13-156-107-56-47-11
Red Wings		17-1210-67-67-69-6

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Sabres		11-13N/AN/A4-67-11
Red Wings		15-11N/AN/A6-78-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 20th@MTLL 2-4+1.5 LU 6.5MTL +124
Oct 18thFLAW 3-0+1.5 WU 5.5BUF +130
Oct 15thOTTW 8-4+1.5 WO 6.5BUF -110
Oct 13thCOLL 1-3+1.5 LU 6.5COL +152
Oct 11th@BOSL 1-3+1.5 LU 5.5BOS -104

Sabres vs. Red Wings Injury Updates

Sabres Injuries

  • Michael Kesselring
    D

    Kesselring is out with lower body

    Out

  • Justin Danforth
    RW

    Danforth is out with lower body

    Out

  • Jiri Kulich
    C

    Kulich is out with ear

    Out

Red Wings Injuries

  • Mason Appleton
    C

    Appleton is out with lower body

    Out

See more NHL Injuries Right Arrow
Team Stats

2
Goals
4
4
Assists
8
5
Penalties
2
28
Shots
31
18
Hits
18
41
Faceoffs Won
32

Red Wings vs. Sabres Odds Comparison

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Red Wings at Sabres Team Totals

MatchupOverUnder
Red Wings
15-11-3
o2.5-165
u2.5+132
Sabres
11-13-4
o3.5+120
u3.5-158