Red Wings vs. Sabres Odds & Betting Predictions - October 22, 2025

Red Wings at Sabres

11:30 pm • TNT

Detroit Red Wings

@

Buffalo Sabres

MatchupOpenSpreadTotalMoneyline
Red Wings 5-1-0	N/A	N/A	N/A
Sabres 2-4-0	N/A	N/A	N/A

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Wednesday 11:30 p.m.

October 22, 2025

KeyBank CenterBuffalo

No props found

NHL Public Betting

Sabres are 2-3 in their last 5 games.
Sabres are 2-3 in their last 5 games against the spread
Sabres are 0-2 in their road games against the spread
The totals have gone OVER in 1 of Sabres' last 5 games
The totals have gone OVER in 1 of Sabres' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Sabres	2-4	2-2	0-2	N/A	2-4
Red Wings	5-1	4-1	1-0	0-1	5-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Sabres	1-5	1-3	0-2	N/A	1-5
Red Wings	2-4	2-3	0-1	0-1	2-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Sabres	2-4	N/A	N/A	N/A	2-4
Red Wings	5-1	N/A	N/A	0-1	5-0

date	opponent	score	spread	over/under	moneyline
Oct 20th	@MTL	L 2-4	+1.5 L	U 6.5	MTL +124
Oct 18th	FLA	W 3-0	+1.5 W	U 5.5	BUF +130
Oct 15th	OTT	W 8-4	+1.5 W	O 6.5	BUF -110
Oct 13th	COL	L 1-3	+1.5 L	U 6.5	COL +152
Oct 11th	@BOS	L 1-3	+1.5 L	U 5.5	BOS -104

Ukko-Pekka Luukkonen
G
Luukkonen is out with lower body
Out
Joshua Norris
C
Norris is out with upper body
Out
Jacob Bryson
D
Bryson is day-to-day with upper body
Day-to-Day
Carson Meyer
RW
Meyer is out with knee
Out
Michael Kesselring
D
Kesselring is out with lower body
Out
Jordan Greenway
LW
Greenway is out with lower body
Out
Justin Danforth
RW
Danforth is out with lower body
Out

Patrick Kane
RW
Kane is day-to-day with upper body
Day-to-Day
Nate Danielson
C
Danielson is out with undisclosed
Out

See more NHL Injuries

3.33

Goals

2.5

2.33

Goals Against

2.5

2.5

Penalties

5.5

27

Shots

29.5

22.17

Hits

22.17

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MatchupOverUnder
Red Wings 5-1-0	N/A	N/A
Sabres 2-4-0	N/A	N/A