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Detroit Red Wings vs Vegas Golden Knights NHL Prediction, Pick, Odds, for Tuesday, November 4

Detroit Red Wings vs Vegas Golden Knights NHL Prediction, Pick, Odds, for Tuesday, November 4 article feature image
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The Detroit Red Wings (9-4-0) and Vegas Golden Knights (6-2-3) meet in the NHL tonight. Puck drop is set for 10:00 p.m. EST at T-Mobile Arena in Las Vegas, Nev. The game will be broadcast live on ESPN+.

The Golden Knights are favored by -1.5 on the puck line, with the over/under set at 6.5 (+105o / -125u). The Golden Knights are a -196 favorite to win outright, while the Red Wings are +162 to pull off the upset.

Let's get into my Red Wings vs. Golden Knights predictions and NHL picks.

Red Wings vs. Golden Knights Odds, Pick

Red Wings Logo
Wednesday, November 5, 2025
10:00 p.m. EST
ESPN+
Golden Knights Logo
Red Wings Odds
SpreadTotalMoneyline
+1.5
-155
6.5
+105o / -125u
+162
Golden Knights Odds
SpreadTotalMoneyline
-1.5
+130
6.5
+105o / -125u
-196
Odds via bet365. Get up-to-the-minute NHL odds here.
bet365 Logo

Red Wings vs. Golden Knights Spread: Golden Knights -1.5 (+130 ), Red Wings +1.5 (-155)

Red Wings vs. Golden Knights Over/Under: 6.5 (+105o / -125u)

Red Wings vs. Golden Knights Moneyline: Red Wings +162, Golden Knights -196

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Red Wings vs. Golden Knights Preview

The "At Home, Quality Opponent, Early Season" NHL moneyline system is built on a simple idea: the early months reward organized home favorites, even when the visitor has a strong record.

In the first couple dozen games, coaches are still experimenting, and the market often leans toward the brand-name road team. However, the home side benefits from last change, familiar boards, and the comfort of routine, while the opponent adjusts to line matchups and travel rhythm.

That combination turns early marquee nights into statement efforts for the favorite, who can roll four lines, dictate matchups, and capitalize on small edges that are harder to find later in the year.

This creates consistent value backing the home favorite against a quality opponent before the season fully settles.


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Red Wings vs. Golden Knights Prediction

Overall, the system stands at 1113-717 (61%) with a 4% ROI across all-time results, and it’s off to a 33-12 (73%) start this season with a 22% ROI.

Best Bet: Golden Knights Moneyline

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