Astros vs. Athletics Odds & Betting Predictions - September 25, 2025

Astros at Athletics

7:35 pm • SCHN

Houston Astros

84-74

5 - 0

Athletics

75-83

MatchupOpenSpreadTotalMoneyline
Astros 84-74	-1.5	-1.5+132	o9.5-110	-119
Athletics 75-83	u9.5	+1.5-162	u9.5-110	-101

Thursday 7:35 p.m.

September 25, 2025

Sutter Health ParkWest Sacramento

Over 9.5-107

1.5u

ATH +104

ATH +102

0.49u

Bet to -105

Under 9.5-105

0.53u

Projecting this closer to 9. Astros still playing for wild card so we’ll get their best. JT Ginn has really impressed with a 4.57 ERA but 3.71 xERA under the hood. I’ll back the pitching here even though it’s a hitter’s ballpark.

Astros vs Athletics: System-Backed Total Pick
Action Network Staff•
Sep 25, 2025 UTC

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No props found

MLB Public Betting

Athletics are 3-2 in their last 5 games.
Athletics are 2-3 in their last 5 games against the spread
Athletics are 47-34 in their road games against the spread
The totals have gone OVER in 1 of Athletics' last 5 games
The totals have gone OVER in 38 of Athletics' 77 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Athletics	85-73	38-39	47-34	14-23	69-48
Astros	79-79	37-44	42-35	40-59	39-18

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Athletics	75-75-8	38-37-2	37-38-6	14-21-2	59-52-6
Astros	71-80-7	36-43-2	35-37-5	44-53-2	25-27-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Athletics	75-83	35-42	40-41	17-20	55-62
Astros	84-74	46-35	38-39	53-46	31-26

date	opponent	score	spread	over/under	moneyline
Sep 25th	HOU	W 6-0	+1.5 W	U 9	ATH +112
Sep 24th	HOU	W 5-1	+1.5 W	U 10	ATH -116
Sep 21st	@PIT	L 0-11	-1.5 L	O 8.5	PIT +100
Sep 20th	@PIT	L 0-2	-1.5 L	U 8	PIT -113
Sep 19th	@PIT	W 4-3	-1.5 L	U 8.5	ATH -112

Luis Medina
SP
Medina is out with elbow
Out
Brady Basso
RP
Basso is out with shoulder
Out

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

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PITCHER		PC	IP	K	ER
LF.Valdez, P		33	3	5	0

HITTERS	H-AB	R	RBI
1J.Altuve, 2B	1-2	1	1
2I.Paredes, DH	1-1	1	1
3C.Correa, 3B	0-1	1	1
4V.Caratini, C	1-2	0	1
5C.Walker, 1B	0-2	0	1
6J.Sanchez, RF	0-2	0	0
7Z.Cole, CF	1-2	1	0
8T.Trammell, LF	1-2	0	0
9M.Dubon, SS	0-1	1	0

PITCHER		PC	IP	K	ER
RJ.Ginn, P		71	3.1	3	5

HITTERS	H-AB	R	HR	RBI
1S.Langeliers, DH	2-2	0	0	0
2J.Wilson, SS	0-2	0	0	0
3T.Soderstrom, LF	0-1	0	0	0
4B.Rooker, RF	0-1	0	0	0
5C.Thomas, CF	0-1	0	0	0
6N.Kurtz, 1B	0-1	0	0	0
7D.Hernaiz, 2B	0-1	0	0	0
8B.Harris, 3B	0-1	0	0	0
9W.MacIver, C	0-0	0	0	0