Cubs vs. Reds Odds & Betting Predictions - May 23, 2025

Cubs at Reds

10:40 pm • MARQ
13 - 6
Starting Pitchers
pitcherteameraw-l
Hunter Greene logoH.GreeneCincinnati Reds logo2.767-4
Matthew Boyd logoM.BoydChicago Cubs logo3.2114-8

Cubs at Reds Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
52-42
-1.5
-1.5+147
o8.5-105
-116
Reds
43-50
u8.5
+1.5-175
u8.5-120
-103
location pinFriday 10:40 p.m.
May 23, 2025
Great American Ball ParkCincinnati
Cubs vs. Reds Expert Picks
Allan Lem
Allan Lem
Last 30d: 38-33-2 (+0.3u)
M.Boyd u5.5 Ks+115
1u
Tailing @The_Oddsmaker
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 57-57-1 (+6.1u)
M.Boyd u5.5 Ks+115
1.15u
Boyd has cleared this line in 4 straight, but that’s largely due to an easier schedule — and this sets up as a sharp sell-high spot. The Reds rank 4th in K% on the season, but today’s lineup projects closer to league average. Boyd’s 24.8% K rate has outpaced his expected mark (21.6% in my model), so some regression looks likely. His best strikeout pitch is the slider (35%+ whiff rate), and while the Reds have struggled badly against sliders (worst whiff rate in MLB), they’re right around league average vs. fastballs, changeups, and curveballs — which is notable because Boyd leans on that mix against right-handed hitters, and the Reds are sending up 8 of them today. His most likely K range is 4–6, and with the under, we win on 2 of those 3 outcomes. I project this closer to -140, making +115 a strong value.
Wags Wins
Wags Wins
Last 30d: 164-170-2 (-22.3u)
M.Boyd o5.5 Ks-127
1.5u
Grant Neiffer
Grant Neiffer
Last 30d: 23-111-4 (-4.3u)
K.Tucker o0.5 HR+380
0.5u
S.Suzuki o0.5 HR+425
2.13u
Cam Is Money
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
CHC -105 (F5)
1u
Austin Pendergrass
Austin Pendergrass
Last 30d: 42-23-2 (+6.4u)
Under 0.5 (1st Inn)-150
0.5u
Doug Ziefel
Doug Ziefel
Last 30d: 148-170-17 (+8.9u)
Under 8.5-110
0.55u
Sean Zerillo
Sean Zerillo
Last 30d: 124-129-6 (-6.5u)
Under 8.5-104
0.52u
Bet to -115
The Propfessor
The Propfessor
Last 30d: 18-40-0 (-2.0u)
M.Boyd o17.5 Outs-130
1.3u

Cubs vs. Reds Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Reds Public Betting Percentages

Away Logo

Cubs

Public

69%

Bets%

31%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Reds
50-4324-2426-1915-1235-30
Cubs
40-5417-2923-2525-3815-16

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Reds
52-40-126-2226-18-118-934-30-1
Cubs
50-4425-2125-2332-3118-13

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Reds
43-5022-2621-2416-1127-38
Cubs
52-4227-1925-2336-2716-15

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 21st@PITL 1-3-1.5 LU 8PIT -128
May 20th@PITL 0-1-1.5 LU 8PIT -145
May 19th@PITW 7-1-1.5 WU 8CIN -116
May 18thCLEW 3-1-1.5 WU 9CIN -135
May 17thCLEW 4-1+1.5 WU 10CIN -105

Reds vs. Cubs Injury Updates

Reds Injuries

    Cubs Injuries

    • Tyler Austin
      1B

      Austin is out with knee

      Out

    • Justin Steele
      SP

      Steele is out with elbow

      Out

    Cubs vs. Reds Box Score
    Cubs Player Stats
    Projected
    PITCHERPCIPKER
    Matthew Boyd logoLM.Boyd, P93434
    Julian Merryweather logoRJ.Merryweather, P320.202
    Chris Flexen logoRC.Flexen, P141.100
    Brad Keller logoRB.Keller, P17110
    Drew Pomeranz logoLD.Pomeranz, P15110
    Ryan Pressly logoRR.Pressly, P16110
    HITTERSH-ABRHRRBI
    Ian Happ logo1I.Happ, LF1-4200
    Kyle Tucker logo2K.Tucker, DH1-5102
    Seiya Suzuki logo3S.Suzuki, RF3-5313
    Pete Crow-Armstrong logo4P.Crow-Armstrong, CF3-5226
    Carson Kelly logo5C.Kelly, C1-4100
    Michael Busch logo6M.Busch, 1B0-4000
    Dansby Swanson logo7D.Swanson, SS1-4112
    Nico Hoerner logo8N.Hoerner, 2B3-5200
    Matt Shaw logo9M.Shaw, 3B0-5100
    Reds Player Stats
    Projected
    PITCHERPCIPKER
    Hunter Greene logoRH.Greene, P83422
    Scott Barlow logoRS.Barlow, P181.130
    Taylor Rogers logoLT.Rogers, P100.200
    Ian Gibaut logoRI.Gibaut, P120.103
    Tony Santillan logoRT.Santillan, P17003
    Brent Suter logoLB.Suter, P351.223
    Luis Mey logoRL.Mey, P23102
    HITTERSH-ABRHRRBI
    TJ Friedl logo1T.Friedl, CF2-5101
    Santiago Espinal logo2S.Espinal, 3B1-4100
    Elly De La Cruz logo3E.De La Cruz, SS1-5100
    Austin Hays logo4A.Hays, LF2-5101
    Spencer Steer logo5S.Steer, 1B3-5101
    Tyler Stephenson logo6T.Stephenson, DH1-4101
    Jose Trevino logo7J.Trevino, C0-2000
    Gavin Lux logo7G.Lux, PH0-0000
    Austin Wynns logo7A.Wynns, C1-1000
    Connor Joe logo8C.Joe, RF1-2000
    Will Benson logo8W.Benson, PH0-2000
    Will Benson logo8W.Benson, RF0-2000
    Matt McLain logo9M.McLain, 2B1-4000

    Cubs vs. Reds Odds Comparison

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    Cubs at Reds Team Totals

    MatchupOverUnder
    Cubs
    52-42
    N/A
    N/A
    Reds
    43-50
    N/A
    N/A