Padres vs. Cardinals Odds & Betting Predictions - July 25, 2025
Padres at Cardinals
11:15 pm • FDSMWStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.84 | 8-11 | ||
![]() | 2.87 | 13-5 |
Padres at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Padres 32-24 | -1.5 | -1.5+134 | o8.5-112 | -130 |
Cardinals 30-25 | u8.5 | +1.5-158 | u8.5-106 | +110 |

Busch StadiumSt. Louis
Padres vs. Cardinals Expert Picks
Picks Office
Last 30d: 133-136-11 (-12.0u)
STL +120
1.2u
Player Prop Savant
Last 30d: 145-119-2 (+19.7u)
SD -136 (F5)
1.36u
Did not mean to play this for full unit - .5u spot
Matt Trollo
Last 30d: 54-62-6 (-6.8u)
STL +110
0.55u
90 degrees - Pivetta 11.4% Barrels/BBE - STL 113/108/115 wRC+ Hm/v RHP/L7 days, SDP 89/99/100 - STL one of best defenses, top bullpen estimators MLB L30 days
Ryan Minion
Last 30d: 329-375-15 (-18.3u)
F.Tatis o1.5 Total Bases-125
$1.00
CeeJ Sports
Last 30d: 0-0-0 (+0.0u)
SD -130
1u
Nick Pivetta, that's it, place the bet. Pivetta is 10-2 with a 2.81 ERA this season and has been the Padres best pitcher. He now will face a Cardinals team that has been all over the place of late.
I would have loved to play a Pivetta ER prop here, but the books are heavily juicing his lines, so the moneyline is a nice 2nd option.
Mikolas will be on the mound for the Cardinals, and I think this Padres lineup can get to him. Mikolas holds a 5-7 record and a 5.20 ERA this season.
This Padres lineup is slowly waking up with guys like Jackson Merrill starting to heat back up, and Mikolas has a favorable pitch mix to provide some run support for Pivetta.
Grant Neiffer
Last 30d: 26-112-5 (+1.1u)
F.Tatis o0.5 HR+400
0.5u
Capper Central
Last 30d: 1-0-0 (+1.0u)
STL +1-118
1u
💰🦡 Jake
Last 30d: 61-70-5 (+2.8u)
SD -1.5+135
1u
Ryan Minion
Last 30d: 329-375-15 (-18.3u)
F.Tatis o1.5 Hits+140
$1.40
SD -140 (F5)
$1.40
Brian Bitler
Last 30d: 95-72-0 (+110.5u)
STL +120
3.6u
Kyle Murray
Last 30d: 21-43-3 (-11.5u)
SD -130 (F5)
1.3u
Padres vs. Cardinals Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Padres vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 1-4 in their last 5 games.
- Cardinals are 2-3 in their last 5 games against the spread
- Cardinals are 17-11 in their road games against the spread
- The totals have gone OVER in 2 of Cardinals' last 5 games
- The totals have gone OVER in 14 of Cardinals' 27 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Cardinals vs. Padres Injury Updates

Cardinals Injuries
- Lars NootbaarLF
Nootbaar is out with heel
Out

Padres Injuries
- Joe MusgroveSP
Musgrove is out with elbow
Out
- Will Wagner3B
Wagner is out with oblique
Out
Padres vs. Cardinals Box Score
Padres Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 90 | 6.1 | 4 | 2 | |
![]() | 6 | 0.2 | 0 | 0 | |
![]() | 9 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
Cardinals Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 73 | 5 | 1 | 0 | |
![]() | 11 | 1 | 0 | 0 | |
![]() | 9 | 1 | 1 | 0 | |
![]() | 9 | 1 | 0 | 0 | |
![]() | 13 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 2-2 | 2 | 0 | 0 |
![]() | 0-3 | 1 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 2 |
![]() | 0-3 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Padres vs. Cardinals Odds Comparison
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Padres at Cardinals Team Totals
MatchupOverUnder | ||
|---|---|---|
Padres 32-24 | N/A | N/A |
Cardinals 30-25 | N/A | N/A |
































