Twins vs Giants Odds: Moneyline, Over/Under, Props - September 21, 2026 | The Action Network

Twins at Giants

1:45 am • NBCS-BA

Minnesota Twins

@

San Francisco Giants

pitcher		team	era	w-l
B.Tidwell			0.00	0-0
B.Ober			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Twins 72-82	N/A	N/A	N/A
Giants 64-90	N/A	N/A	N/A

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Tuesday 1:45 a.m.

September 22, 2026

Oracle ParkSan Francisco

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62°Fahrenheit

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0%Rain

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9Wind

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MLB Public Betting

Giants are 2-3 in their last 5 games.
Giants are 3-2 in their last 5 games against the spread
Giants are 39-40 in their road games against the spread
The totals have gone OVER in 4 of Giants' last 5 games
The totals have gone OVER in 36 of Giants' 75 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	77-77	38-37	39-40	21-27	55-49
Twins	77-77	38-40	39-37	22-32	53-44

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	74-70-10	36-36-3	38-34-7	27-18-3	46-51-7
Twins	84-63-7	38-36-4	46-27-3	27-26-1	55-36-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	64-90	36-39	28-51	24-24	39-65
Twins	72-82	40-38	32-44	28-26	42-55

date	opponent	score	spread	over/under	moneyline
Sep 19th	@LAD	L 2-8	+1.5 L	O 8.5	LAD +257
Sep 16th	@STL	W 6-5	+1.5 W	O 8.5	SF +140
Sep 15th	@STL	W 10-3	+1.5 W	O 8.5	SF +153
Sep 14th	@STL	L 1-2	+1.5 W	U 8	STL +127
Sep 13th	SD	L 4-6	+1.5 L	O 7.5	SD +120

Pablo Lopez
SP
Lopez is out with elbow
Out
David Festa
SP
Festa is out with shoulder
Out
Travis Adams
SP
Adams is out with triceps
Out

Hayden Birdsong
SP
Birdsong is out with arm
Out

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MatchupOverUnder
Twins 72-82	N/A	N/A
Giants 64-90	N/A	N/A