Twins vs. Giants Odds & Betting Predictions - September 22, 2026
Twins at Giants
1:45 am • NBCS-BAStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.45 | 1-2 | ||
![]() | 4.90 | 9-11 |
Twins at Giants Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Twins 0-0 | -1.5 | -1.5+134 | o8-109 | -133 |
Giants 0-0 | u8 | +1.5-157 | u8-110 | +110 |

Oracle ParkSan Francisco
Twins vs. Giants Expert Picks
Kyle Murray
Last 30d: 136-150-7 (+0.5u)
Z.Matthews o4.5 Ks-105
1u
Adam Kaufman
Last 30d: 333-306-16 (-16.4u)
MIN -115
1.15u
Scott Rickenbach
Last 30d: 99-90-2 (-1.2u)
Over 4.5 (F5)-120
0.83u
Charlie DiSturco
Last 30d: 118-237-2 (-3.1u)
Z.Matthews o4.5 Ks-108
0.5u
Z.Matthews To Record 6+ Strikeouts Yes+196
0.49u
tonysartori99
Last 30d: 13-12-0 (+3.5u)
Over 8-118
1u
Twins vs. Giants Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Twins vs. Giants Public Betting Percentages
Betting Trends
- Giants are 0-5 in their last 5 games.
- Giants are 2-3 in their last 5 games against the spread
- Giants are 39-42 in their road games against the spread
- The totals have gone OVER in 0 of Giants' last 5 games
- The totals have gone OVER in 36 of Giants' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Twins vs. Giants Injury Updates

Twins Injuries
- Pablo LopezSP
Lopez is out with elbow
Out
- David FestaSP
Festa is out with shoulder
Out
- Travis AdamsSP
Adams is out with triceps
Out

Giants Injuries
- Hayden BirdsongSP
Birdsong is out with arm
Out
Twins vs. Giants Box Score
Twins Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 100 | 5 | 9 | 5 | |
![]() | 25 | 1.1 | 1 | 0 | |
![]() | 20 | 1.2 | 3 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
Giants Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 57 | 3.1 | 4 | 1 | |
![]() | 32 | 2.2 | 1 | 0 | |
![]() | 20 | 1 | 2 | 0 | |
![]() | 9 | 1 | 0 | 1 | |
![]() | 16 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 3-4 | 2 | 1 | 3 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 2 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
Twins vs. Giants Odds Comparison
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Twins at Giants Team Totals
MatchupOverUnder | ||
|---|---|---|
Twins 0-0 | N/A | N/A |
Giants 0-0 | N/A | N/A |




























