Astros vs Mariners Odds, Pick | How to Bet the Moneyline

Wednesday, May 29

9:40 p.m. ET

MLB.TV

Astros Odds
Moneyline	Total	Run Line
-102	7 -118o / -104u	-1.5 +162

Mariners Odds
Moneyline	Total	Run Line
-116	7 -118o / -104u	+1.5 -196

Odds via FanDuel. Get up-to-the-minute MLB odds here.

The Seattle Mariners have captured each of the first two games against the Houston Astros in a pair of low-scoring victories.

The two American League West rivals continue their series at T-Mobile Park as Seattle looks to extend its lead atop the division when it faces a former Cy Young winner tonight.

So, where does the betting value lie? Let's make an Astros vs. Mariners pick after looking at the MLB odds for Wednesday, May 28.

Houston Astros

The Astros won six consecutive games in mid-May, and it looked like a turnaround for the three-time defending AL West champions may have been coming. However, Houston split six games against the two teams below it in the division recently before taking two out of three at Oakland this past weekend.

The offense was limited to two runs in each of the first two losses at Seattle. The Mariners jumped out to a 3-0 lead in Monday's opener and held off the Astros, 3-2.

On Tuesday, Houston held a 2-1 advantage headed to the eighth inning before Seattle busted out for three runs, capped off by a two-run single from outfielder Julio Rodriguez to lift the M's to a 4-2 win.

Justin Verlander looks to stop the bleeding for Houston, as the future Hall-of-Famer has performed better on the road than at home this season.

Verlander's road ERA sits at 3.18, compared to 4.63 at Minute Maid Park. The Astros are also 3-2 in his road starts compared to an 0-2 mark at home.

Verlander is coming off a season-high nine strikeouts against the Athletics his last time out, marking the third over on his K prop in his past four road starts.

Last season, Verlander dominated the Mariners at T-Mobile Park by tossing eight innings and allowing three hits and one run in a 5-1 triumph as a short underdog.

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Seattle Mariners

The Mariners moved to 4-1 against the Astros this season with last night's victory, improving to 13-4 in their last 17 games at T-Mobile Park.

George Kirby takes the mound for Seattle, looking to get on track after a pair of subpar starts. Kirby yielded five runs in each of his last two outings at Baltimore and Washington while giving up two home runs each time.

The right-hander has been significantly better at home this season, posting a 4-1 record and 2.97 ERA at T-Mobile Park.

Kirby hasn't given up a run in his past two home outings against the Royals and Diamondbacks and has struck out at least six batters in four of his past five home starts.

Earlier this season, Kirby silenced the Astros in six innings, allowing only one run at Minute Maid Park on May 3. Seattle led Houston, 3-1, headed to the seventh inning before the Astros rallied for four runs in a 5-3 win.

In his last three starts against Houston dating back to 2023, Kirby has given up two runs in a total of 18 2/3 innings. Seattle owns a 2-1 record in those games.

The Mariners are on a 5-1 under run in their past six games, while Seattle has allowed two runs or fewer in four of their past five home contests.

Astros vs Mariners

Betting Pick & Prediction

Kirby should put together a better performance tonight simply being back at home after already shutting the Astros down several times in his last few matchups against Houston.

Houston's offense has struggled against Seattle's starting pitching this season and just hasn't gotten going. Verlander is tough to go against as a short underdog, but there's no need to jump off the Mariners at home right now.

Pick: Mariners Moneyline -112 (Play to -120)