The Boston Red Sox host the Baltimore Orioles on July 22, 2026. First pitch from Fenway Park is scheduled for 7:10 p.m. EDT. The game will be broadcast on MASN.
The Red Sox are favored by -132 on the moneyline and by -1.5 on the run line. The Orioles are +112 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Orioles vs Red Sox prediction below, as well as probable pitchers, weather report, and more.
Orioles vs Red Sox Odds
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -178 | 8.5 -122o / -100u | +112 |
| Red Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +146 | 8.5 -122o / -100u | -132 |
Orioles vs Red Sox Probable Pitchers
| Kyle Bradish (RHP, BAL) | Stat | TBA |
|---|---|---|
| 6-9 | W-L | — |
| 1.5 | fWAR (FanGraphs) | — |
| 3.61 / 3.83 | ERA / xERA | — |
| 4.01 / 3.99 | FIP / xFIP | — |
| 12.3% | K-BB% | — |
| 48.8% | GB% | — |
| .291 | BABIP | — |
| 101 | Stuff+ | — |
| 100 | Location+ | — |
Orioles vs Red Sox MLB Betting Preview
The Red Sox will go for a franchise-record-breaking 16 wins tonight in Game 2 of their home doubleheader against the Orioles.
We've broken down this matchup every which way, so check out some of our Best Bets for the MLB game tonight.
Orioles vs Red Sox Predictions, Picks
For starters, it's always wise to use BARTOLO when handicapping any matchup.
Sean Zerillo's new PRO baseball betting tool gives all our PRO subscribers access to all the data he uses to project MLB games each day. Here's a sneak peek of what BARTOLO looks like for this Sox-Orioles game:
As you can see, Zerillo shows some value on the Red Sox to claim their 16th straight victory.
Orioles vs Red Sox Betting Trends
Here's where all the money is going for this matchup:
Orioles vs Red Sox Top Player Props
If you can't find any value on the side or the total, it's always wise to dive into the player prop markets.
Our PRO tools are constantly updating projected prop totals for MLB players, providing you with live feedback on where the largest prop edges lie.
Here are a few top props for this Game 2 matchup:
