Red Sox vs Athletics Prediction, Pick, Odds for Wednesday, September 10 article feature image
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Red Sox vs Athletics Prediction, Pick, Odds for Wednesday, September 10

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Pictured: Payton Tolle. (Credit: Rick Scuteri-Imagn Images)

The Athletics host the Boston Red Sox on September 10, 2025. First pitch from Sutter Health Park is scheduled for 3:35 p.m. EDT; the game will be broadcast on NBCS-CA.

Find my MLB betting preview and Red Sox vs Athletics prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Red Sox vs Athletics Prediction

  • Red Sox vs Athletics pick: Payton Tolle Under 5.5 Strikeouts

My Red Sox vs Athletics best bet is backing Tolle to stay under 5.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.


Red Sox vs Athletics Odds

Red Sox Logo
Wednesday, Sep 10
3:35 p.m. ET
NBCS-CA
Athletics Logo
Red Sox Odds
SpreadTotalMoneyline
-1.5
+112
10.5
-108o / -112u
-132
Athletics Odds
SpreadTotalMoneyline
+1.5
-137
10.5
-108o / -112u
+108
Odds via DraftKings. Get up-to-the-minute MLB odds here.
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Red Sox vs Athletics Projected Starting Pitchers

LHP Payton Tolle (BOS)StatRHP Mason Barnett (ATH)
0-1W-L1-1
-0.1fWAR (FanGraphs)0.1
7.56/5.99ERA /xERA9.00/3.94
6.02/4.74FIP / xFIP4.59/5.36
1.68WHIP1.78
10.5%K-BB%9.3%
22.7%GB%28.6%
116Stuff+98
84Location+95

Charlie Wright’s Prediction, Betting Analysis

This is a bet against the workload for Tolle. He was originally expected to follow an opener, but it sounds like he’ll make a traditional start instead. This will be his first start of the season on four days' rest, and multiple reports have suggested it will be an abbreviated outing.

Kyle Harrison has been floated as a potential option after Tolle. Dustin May hit the IL and Harrison is expected to be the corresponding move.

The Athletics have the 8th-highest K% vs. LHP since the start of July, but they also have the highest OPS and the 2nd-highest wOBA. It’s a dangerous matchup.

Pick: Payton Tolle Under 5.5 Strikeouts (-134, DraftKings)


Red Sox vs Athletics Betting Trends



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Charlie WrightStaff Writer

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