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Cardinals vs A’s Prediction, Pick, MLB Odds for Wednesday, May 13

Cardinals vs A’s Prediction, Pick, MLB Odds for Wednesday, May 13 article feature image
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May 10, 2026; San Diego, California, USA; St. Louis Cardinals right fielder Jordan Walker (18) points skyward after hitting two-run home run during the fourth inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

The Athletics host the St. Louis Cardinals on May 13, 2026. First pitch from Sutter Health Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on NBCS-CA.

The Athletics are favored by -152 on the moneyline and by -1.5 on the run line. The Cardinals are +128 on the moneyline and +1.5 on the run line. The total is set at 10 runs.

Find my MLB picks and Cardinals vs Athletics prediction below, as well as probable pitchers, weather report, and more.


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Cardinals vs Athletics Prediction

  • Cardinals vs Athletics Pick: Cardinals ML (+120 or Better)

My Cardinals vs Athletics best bet is on St. Louis to win. Make sure to find the best odds by checking our live MLB odds page.


Cardinals vs Athletics Odds

Cardinals Logo
Wednesday, May 13
9:40 p.m. ET
NBCS-CA
Athletics Logo
Cardinals Odds
SpreadTotalMoneyline
+1.5
-154
10
-105o / -115u
+128
Athletics Odds
SpreadTotalMoneyline
-1.5
+128
10
-105o / -115u
-152
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Cardinals vs Athletics moneyline: Cardinals +128, Athletics -152
  • Cardinals vs Athletics over/under: 10 (-105 / -115)
  • Cardinals vs Athletics spread: Athletics -1.5 (+128), Cardinals +1.5 (-154)

Cardinals vs Athletics Probable Pitchers

Matthew Liberatore (LHP, STL)StatJ.T. Ginn (RHP, ATH)
2-1W-L1-1
-0.2fWAR (FanGraphs)0.3
4.07 / 5.49ERA / xERA3.62 / 3.66
5.36 / 4.69FIP / xFIP4.48 / 4.02
7.3%K-BB%10.7%
38.3%GB%51.0%
.286BABIP.224
99Stuff+96
100Location+102

Cardinals vs Athletics MLB Betting Preview

This game triggered one of our Action PRO betting systems, powered by Evan Abrams:

This game triggered one of our Action PRO betting systems, powered by Evan Abrams:

In Major League Baseball, road underdogs playing interleague games have historically been undervalued by oddsmakers.

Since 2016, despite winning only 43.1% of these games, these teams have generated a consistent positive ROI.

This trend has proven reliable across five consecutive seasons, indicating market inefficiencies in how these specific matchups are priced — likely due to lack of familiarity between leagues and public overconfidence in home and favorite teams.


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Cardinals vs Athletics Pick, Betting Analysis

Although the A's are on top of the AL West, the Cardinals continue to be frisky, holding the better record (22-20) and run differential (+5).

The RedBirds have a high-upside lineup behind Jordan Walker, a rock-solid defense, and the better bullpen in this matchup.

Pick: Cardinals ML (+120 or Better)


Cardinals vs Athletics Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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