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Reds vs Yankees Prediction, Pick, MLB Odds for Sunday, June 21

Reds vs Yankees Prediction, Pick, MLB Odds for Sunday, June 21 article feature image
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May 9, 2026; Cincinnati, Ohio, USA; Cincinnati Reds starting pitcher Chase Burns (26) prepares to pitch against the Houston Astros in the first inning at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

The New York Yankees host the Cincinnati Reds on June 21, 2026. First pitch from Yankee Stadium is scheduled for 1:35 p.m. EDT. The game will be broadcast on YES.

The Yankees are favored by -126 on the moneyline and by -1.5 on the run line. The Reds are +104 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Reds vs Yankees prediction below, as well as probable pitchers, weather report, and more.


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Reds vs Yankees Prediction

  • Reds vs Yankees Pick: Under 8.5 (-110 | Play to -115)

My Reds vs Yankees best bet is Under 8.5. Make sure to find the best odds by checking our live MLB odds page.


Reds vs Yankees Odds

Reds Logo
Sunday, Jun 21
1:35 p.m. ET
YES
Yankees Logo
Reds Odds
SpreadTotalMoneyline
+1.5
-205
8.5
-104o / -116u
+104
Yankees Odds
SpreadTotalMoneyline
-1.5
+168
8.5
-104o / -116u
-126
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Reds vs Yankees moneyline: Reds +104, Yankees -126
  • Reds vs Yankees over/under: 8.5 (-104o / -116u)
  • Reds vs Yankees spread: Reds +1.5 (-205), Yankees -1.5 (+168)

Reds vs Yankees Probable Pitchers

Chase Burns (RHP, CIN)StatElmer Rodriguez (RHP, NYY)
8-1W-L0-1
2.5fWAR (FanGraphs)0.0
2.01ERA / xERA4.15 / 6.22
3.16 / 3.29FIP / xFIP4.94 / 6.79
21.6%K-BB%-4.7%
38.5%GB%48.9%
.249BABIP.326
114Stuff+89
101Location+88

Reds vs Yankees MLB Betting Preview

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Cincinnati Reds Betting Preview

Right-hander Chase Burns takes the mound for the Reds on Sunday and should be a strong candidate to back. The second overall pick in the 2024 MLB Draft, Burns entered the league last season with high expectations.

He struggled in a limited sample, but those concerns have been alleviated by his dominant start to 2026. Through 14 starts, Burns is 8-1 with a 2.01 ERA and a 1.02 WHIP.

His underlying metrics are equally impressive. Entering this matchup, the right-hander ranks in the 87th percentile or higher in xERA, xBA and strikeout rate.

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New York Yankees Betting Preview

That said, run support may be difficult to come by for Burns. This season, Cincinnati ranks in the bottom half of the league in runs scored per game, hits per game, slugging percentage and OPS.

The Reds’ struggles at the plate are likely to continue against right-hander Elmer Rodriguez, who gets the ball for the  Yankees. Rodriguez was optioned to the minors in May after Gerrit Cole returned from injury, but he left on a high note.

In that outing, Rodriguez allowed just one run across nearly five innings against the New York Mets. He continued to pitch well during his time in Triple-A, posting a 3.00 ERA and a 1.22 WHIP through 10 starts.


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Reds vs Yankees Pick, Betting Analysis

It is a favorable opportunity for Rodriguez to build on that success following his most recent call-up, given Cincinnati’s offensive struggles. Over their past 10 games, the Reds own a .707 OPS.

Of course, the biggest obstacle to the under is the Yankees’ powerful lineup. That said, Burns has been one of the best pitchers in baseball this season and has allowed two or fewer runs in each of his past 11 starts.

Pick: Under 8.5 (-110 | Play to -115)


Reds vs Yankees Weather


Get the latest coverage on MLB Weather.

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