Guardians vs Giants Predictions, F5 Pick, Odds

Guardians vs Giants Predictions, F5 Pick, Odds article feature image
Credit:

Ron Chenoy-Imagn Images.
Pictured: Robbie Ray.

Starting soon
Odds Updating Soon
Matchup - 6/18 1:45am UTCSpreadTotalMoneyline
+1.5-171
o7-121
+129
-1.5+141
u7+100
-158

The San Francisco Giants (41-31) host the Cleveland Guardians (35-35) on Tuesday, June 17, 2025. First pitch from Oracle Park is scheduled for 9:45 p.m. ET; the game will be broadcast on NBC Sports Bay Area and Guardians TV.

It's a big Tuesday in the Bay Area as Rafael Devers is set to make his debut for the Giants since getting traded from the Boston Red Sox.

Find my Guardians vs Giants prediction and pick on the first five innings (F5) below, as well as probable pitchers, betting trends and more.


Guardians vs Giants Prediction, Odds, Spread, Over/Under

Guardians Logo
Tuesday, Jun 17
9:45 p.m. ET
CLEG
Giants Logo
Guardians Odds
SpreadTotalMoneyline
+1.5
-170
7
-120o / 100u
+130
Giants Odds
SpreadTotalMoneyline
-1.5
+143
7
-120o / 100u
-155
Odds via Caesars. Get up-to-the-minute MLB odds here.
Caesars Logo

Guardians vs Giants Projected Starting Pitchers

RHP Slade Cecconi (CLE)StatLHP Robbie Ray (SF)
1-3W-L8-1
0.0fWAR (FanGraphs)1.8
4.26/ 5.87ERA /xERA2.55/ 2.83
5.00/ 3.81FIP / xFIP2.98/ 3.59
1.26WHIP1.12
18.3%K-BB%18.0%
33.8%GB%40.2%
94Stuff+102
109Location+96

Guardians vs Giants Preview, Prediction

Header First Logo

Guardians Betting Preview: Road Woes

Slade Cecconi gets the ball for the Guardians tonight. Cecconi has flashed moments of dominance in 2025, especially via the strikeout.

Cecconi has a 4.26 ERA, but sports a 5.87 xERA. That is concerning, as it appears that regression is looming.