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MLB Best Bets Today: Predictions & Picks for Reds vs Phillies, Dodgers vs Padres, More for Wednesday, May 20

MLB Best Bets Today: Predictions & Picks for Reds vs Phillies, Dodgers vs Padres, More for Wednesday, May 20 article feature image
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Credit:

May 18, 2026; San Diego, California, USA; San Diego Padres second baseman Fernando Tatis Jr. (23) celebrates after center fielder Jackson Merrill (3) made a catch on a ball hit by Los Angeles Dodgers third baseman Max Muncy (13) during the seventh inning at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

We have a full 15-game slate today, starting early with Reds vs Phillies at 1:05 PM at Citizens Bank Park Park on MLB.TV, and closing with Dodgers vs Padres at 8:40 p.m. ET at PetCo Park on MLB.TV.

Our experts have analyzed the matchups and found great options for Wednesday.

Below are 4 expert MLB best bets today.


MLB Best Bets Today

The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

GameTime (ET)Pick
Cincinnati Reds LogoPhiladelphia Phillies Logo
1:05 PM
Chicago White Sox LogoSeattle Mariners Logo
3:10 PM
Atlanta Braves LogoMiami Marlins Logo
6:40 PM
Los Angeles Dodgers LogoSan Diego Padres Logo
8:40 PM
Action Logo
All Day
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.


Tanner McGrath's Reds vs Phillies Best Bet

Cincinnati Reds Logo
Wednesday, May 20
1:05 PM ET
MLB.TV
Philadelphia Phillies Logo
Over 10 (-105 or Better)
FanDuel Logo

By Tanner McGrath

Our own Sean Zerillo projects value on the Over in this matchup.

While the consensus line sits around 10, he projects the number closer to 10.4. And, as logged in the Action App, he recommends betting the Over 10 at -105 or better.

As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.

Additionally, our own Matt Trollo bet the Over as well, citing the positive hitting weather (+11%, per BallParkPal), two sloppy defenses, Andrew Abbott's poor earned run estimators (all over 4.5), and Cincinnati's recent bullpen implosion.

While all of Trollo's points stand, I also want to add that Aaron Nola has looked like a shell of himself this season.

He may be due for some positive regression (5.91 ERA, 3.86 xFIP), given his decent fastball velocity and 23% strikeout rate (alongside a tough .344 BABIP). However, his batted-ball profile is a mess, and he can't locate the ball (career-low 97 in Location+).

I love this early-afternoon Over.

Pick: Over 10 (-105 or Better)



Evan Abrams's White Sox vs Mariners Best Bet

Chicago White Sox Logo
Wednesday, May 20
3:10 PM ET
MLB.TV
Seattle Mariners Logo
Mariners ML (-160 or Better)
FanDuel Logo

By Evan Abrams

This game triggered one of our Action PRO betting systems:

MLB Icon
Evan Abrams / Bet Labs – Market Movers in Conference Clashes
the team's previous game margin is between -9 and 4
the game is a Conference game
the moneyline change from open to close is between -33 and -1
the opening moneyline is between -145 and -115
the team's Pythagorean +/- is between 1.6% and 500%
the opening total is between 7 and 9.5
$9,434
WON
1413-922-0
RECORD
61%
WIN%

This system tracks modest favorites in conference games where the market slightly shifts toward them, often because subtle edge signals are not captured by public models.

Minor moneyline movement (−33 to −1) from open to close shows quiet but meaningful sharp action.

The Pythagorean advantage (over 1.6%) confirms the underlying team quality without large margins in the prior game.

Opening lines between −145 and −115 suggest limited public interest, creating pricing inefficiencies.

Totals between 7 and 9.5 help avoid extremes that can skew results.

The strategy rides light market momentum in tight, competitive spots where fundamental metrics signal a long-term edge.

Pick: Mariners ML (-160 or Better)



Sean Paul's Braves vs Marlins Best Bet

Atlanta Braves Logo
Wednesday, May 20
6:40 PM ET
MLB.TV
Miami Marlins Logo
Braves -1.5 (-105 or Better)
FanDuel Logo

By Sean Paul

The Braves have been excellent all year. Their record stands at a terrific 32-16, and they hold a commanding lead for first place in the NL East.

Chris Sale has evaded Father Time thus far. He might be 37 years old, but he looks 27, boasting a 1.96 ERA in nine starts. Sale's underlying numbers are shaky, though. He has a 3.07 xERA and a 3.23 FIP. I don't think Sale will maintain a sub-2.00 ERA, but he'll continue to contend for the NL CY Young.

May has been a down month for the Braves' offense, posting a 100 wRC+ compared to their 113 for the season. Still, their May wRC+ puts them 11th in MLB. Power fuels this Atlanta offense, as it has 23 homers this month, good for fourth in the league.

It's worth noting that the Braves didn't have Ronald Acuna Jr. from May 3rd to May 17th. He might not replicate his 40/70 season, but Acuna can set the table for Matt Olson and Drake Baldwin to drive in runs.

My one issue with the Braves is their lack of walks: they rank 26th this year with a 7.8% walk rate. They strike out just 20% of the time, which means this lineup is looking to swing. But pitchers can go longer in games against free-swinging lineups.

Things have trended very poorly for Marlins hurler Janson Junk of late. In his past two outings, he gave up seven runs to the Rays in 5 2/3 and four to the Nationals in six innings.

For the year, Junk has a 4.14 ERA, a 3.79 xERA, and a 4.20 FIP. He's a solid back-end of the rotation arm who got all of his regression in his last two outings.

However, I question his long-term viability as an MLB starter due to his lack of raw stuff. Out of 74 qualified starters, Junk is tied with the Rockies' Michael Lorenzen for the 15th-lowest K/9 in MLB. Junk sits in the 22nd percentile in strikeout rate and 14th in whiff rate. Plus, he gets hit hard, as he ranks in the 30th percentile or worse in average exit velocity and hard hit rate.

The Marlins are about as league-average an offense as there is. And I mean that in the nicest way possible.

Miami lacks the explosiveness to be a top-10 offense for a month, but it ranks 17th in MLB this year and 16th in May. Consistency is a huge key, and the top of the Marlins order keeps them consistent. Xavier Edwards and Otto Lopez have done a terrific job getting in scoring position for Liam Hicks and Kyle Stowers to drive them in.

The issue? Stowers and Hicks have struggled in May, and both struggle against lefties in general. Hicks is hitting just .241 against southpaws while Stowers checks in with a .227 average.

I'm rolling with Atlanta on the run line here. The moneyline is juiced too much to give it out, and I think Atlanta provides its ace with run support, which he didn't get in his past two outings. That's why losses are a totally meaningless pitcher stat. Sale lost his last two outings, but shut the Dodgers and Padres down. The Braves scored just one run in those 18 innings.

Sale has the weapons to slow down this Marlins lineup, and Junk's recent outings have shown his implosion potential — and the Braves could erupt for a lopsided scoring night.

Pick: Braves -1.5 (-105 or Better)



Ryan Minion's Dodgers vs Padres Best Bet

Los Angeles Dodgers Logo
Wednesday, May 20
8:40 PM ET
MLB.TV
San Diego Padres Logo
NRFI (-130 or Better)
FanDuel Logo

By Ryan Minion

The Dodgers’ Wednesday night starter needs no introduction, as superstar two-way player Shohei Ohtani will look to build upon his phenomenal form over his first seven outings this season.

Though not as dominant as Ohtani, Padres’ 27-year-old righty Randy Vasquez has been rather impressive as well across nine starts thus far.

While the Dodgers are coming off consecutive World Series victories over the past two seasons, their Japanese superstar had been unable to pitch until this season after recovering from surgery on his right throwing elbow.

Many were unsure what to expect from Ohtani upon his return to the mound this season, given his extended leave away from pitching, yet baseball’s first two-way star since the great Babe Ruth has more than delivered on his tremendous hype as a dual threat.

Shohei has recorded an exceptional 0.82 ERA on the season across his first 44 frames on the mound, with baseball’s biggest star having allowed just four ER in 2026.

Any form of preseason concern about Ohtani’s pitching form has since been wiped clean, and I expect the Dodgers’ superstar to continue his reign of dominance on the mound thus far.

While Vasquez is far from Ohtani’s pitching metrics to start the season, he ranks inside the top-20 in baseball with a 2.68 ERA across his first nine starts of the season.

Though the Friars’ right-hander has shown some susceptibility to damage at times this season, he has been very reliable as of late, having allowed just 1 ER over his last 11 innings pitched (IP).

I favor no runs to be scored in the first inning (NRFI) of Wednesday night’s NL West showdown.

Pick: NRFI (-130 or Better)



Sean Zerillo's Action App Card for Wednesday

Need more picks for Wednesday's all-day action? It's always wise to see what our guy Zerillo is betting on!

Make sure to follow him in the Action App to get all his MLB picks.



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