The Pittsburgh Pirates host the San Diego Padres on April 7, 2026. First pitch from PNC Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on SportsNet PT.
The Pirates are favored by -158 on the moneyline and by -1.5 on the run line. The Padres are +134 on the moneyline and +1.5 on the run line. The total is set at 6.5 runs.
Find my MLB picks and Padres vs Pirates prediction below, as well as probable pitchers, weather report, and more.
Padres vs Pirates Prediction
- Padres vs Pirates Pick: Under 6 (+100 or Better)
My Padres vs Pirates best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Pirates Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -178 | 6.5 -104o / -118u | +134 |
| Pirates Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +146 | 6.5 -104o / -118u | -158 |
- Padres vs Pirates spread: Pirates -1.5 (+146), Padres +1.5 (-178)
- Padres vs Pirates over/under: 6.5 (-104o / -118u)
- Padres vs Pirates moneyline: Padres +134, Pirates -158
Padres vs Pirates Pitchers
| Nick Pivetta (RHP) | Stat | Paul Skenes (RHP) |
|---|---|---|
| 1-1 | W-L | 1-1 |
| 0.3 | fWAR (FanGraphs) | 0.1 |
| 6.75 / 3.36 | ERA / xERA | 9.53 / 2.35 |
| 2.05 / 4.64 | FIP / xFIP | 3.71 / 6.15 |
| 1.63 | WHIP | 1.94 |
| 18.9% | K-BB% | 6.9% |
| 53.8% | GB% | 27.8% |
| 103 | Stuff+ | 100 |
| 98 | Location+ | 104 |
Padres vs Pirates MLB Betting Preview
Padres vs Pirates Picks
The Pirates don't play until Tuesday evening, but conditions will be similarly suppressive for offense at PNC Park, with 43 degrees at first pitch and mid-30s by midgame.
The wind is blowing out to right field, which reduced my downward projected weather adjustment.
However, I would still have made this game around 7 on a weather-neutral day and set it closer to 5.75 with an excellent pitching matchup in cold weather.
Pick: Under 6 (+100 or Better)
