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Giants vs Dodgers Prediction, Pick, Odds: Long-Shot Plus-Money MLB Underdog Bet

Giants vs Dodgers Prediction, Pick, Odds: Long-Shot Plus-Money MLB Underdog Bet article feature image
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Photo Credit: Scott Marshall-Imagn Images
Pictured: Adrian Houser throws

The Los Angeles Dodgers host the San Francisco Giants on May 12, 2026. First pitch from UNIQLO Field at Dodger Stadium is scheduled for 10:10 p.m. EDT. The game will be broadcast on NBCS-BA.

The Dodgers are favored by -310 on the moneyline and by -1.5 on the run line. The Giants are +250 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Giants vs Dodgers prediction below, as well as probable pitchers, weather report, and more.


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Giants vs Dodgers Prediction

  • Giants vs Dodgers Pick: Giants ML (+250, FanDuel)

My Giants vs Dodgers best bet is on San Francisco to win. Make sure to find the best odds by checking our live MLB odds page.


Giants vs Dodgers Odds

Giants Logo
Tuesday, May 12
10:10 p.m. ET
NBCS-BA
Dodgers Logo
Giants Odds
SpreadTotalMoneyline
+1.5
+122
8.5
-110o / -110u
+250
Dodgers Odds
SpreadTotalMoneyline
-1.5
-146
8.5
-110o / -110u
-310
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Giants vs Dodgers moneyline: Giants +250, Dodgers -310
  • Giants vs Dodgers over/under: 8.5 (-110o / -110u)
  • Giants vs Dodgers spread: Dodgers -1.5 (-146), Giants +1.5 (+122)

Giants vs Dodgers Polymarket Odds

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Giants vs Dodgers Probable Pitchers

Adrian HouserStatYoshinobu Yamamoto
16-24W-L24-16
-0.2fWAR (FanGraphs)0.9
6.19 / 5.53ERA / xERA3.09 / 4.26
5.57 / 4.57FIP / xFIP3.53 / 3.52
4.8K-BB%17.6
48.1GB%41.9
.297BABIP.254
92Stuff+101
112Location+107

Giants vs Dodgers MLB Betting Preview

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San Francisco Giants Betting Preview: Bats Waking Up

Things are improving ever so slightly for the Giants. They've won three of four, and their offense has exploded for 16 runs across their last two games. In the last week, we've seen a drastic rise in walks for San Francisco, which is recording a 10% walk rate, with a further drop in strikeouts. This is quite the turnaround considering their 5.7% walk rate and 21.3% strikeout rate for the year, not to mention their brutal .120 Isolated Power.

San Francisco is beginning to find some pop and patience at the plate, and now with Harrison Bader healthy, Bryce Eldridge joining the lineup and Jung-Hoo Lee beginning to hit, this looks like a real offense.

The team will be hoping Adrian Houser has found something as well. He reeled off his best start of the year last week against the Padres, working six innings of one-run ball with just one walk and three punchouts, and while he did allow a home run, it was one of just three hits against him.

Houser has done a good job of keeping the ball out of the air once again this year, but as such a low-strikeout arm, he's going to be susceptible to some long balls. His hard-hit rate still stands at an ugly 45.9% with a .506 Expected Slugging Percentage, and with his defense posting a -1 Outs Above Average so far this year, the upside may be limited.

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Los Angeles Dodgers Betting Preview: Dominance Has Slipped

The Dodgers will counter with Yoshinobu Yamamoto, who has been a little less than his best this season. Things don't look all that terrible on the surface, with the right-hander posting a 3.09 ERA — up 60 points from last season, but still good — and a 1.01 WHIP. Other than that, though, this model of consistency has been all over the place in 2026.

Yamamoto turned in a season-best eight strikeouts last start against the Astros, but his punchout rate remains at a weak 23.5% by his standards. He was nearing 30% over the last two seasons, something quite unnecessary with the way he was getting outs on contact, but suddenly the Ks have become essential with his otherwise weak profile.

The righty's biggest issue has been keeping the ball out of the air. His Pull Air% has jumped from an elite 12.1% to 21.8% this season, and his overall rate of contact in the air has jumped 13.4 points. It's not as if opponents are hitting the ball harder off Yamamoto — they're just hitting it in a more precarious place — and that's led to a terrible .444 xSLG.

The third-year big leaguer remains a stalwart in the walks department, but either the ground balls or strikeouts — ideally both — are going to have to return. His ground-ball rate has been over 50% in three of his last five starts, however, so perhaps we just have to wait for a larger sample before pressing the panic button.


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Giants vs Dodgers Pick, Betting Analysis

The good news for Yamamoto is that the Giants put the ball on the ground a lot. They rank fifth in ground-ball rate this season, and despite their recent uptick in power and production over the last week, they still own a 44.4% ground-ball rate, which is slightly above average.

They may not be striking out a bunch, which will hurt Yamamoto here, but the Giants are just 21st in Pull Air% this year to boot and are playing in an arduous stadium for homers. This should help Yamamoto settle back down, but I'm not sure it means the Dodgers win this game.

Without the threat of many home runs, at least for San Francisco, it's hard to play the over here despite seeing flaws with the better pitcher and getting Houser on the other side of the matchup. With that said, the Dodgers are hitting just .225 over the last week with a terrible 6.5% walk rate and 25.7% strikeout rate, signaling the team is in a bad spot at the moment.

Even with some gaudy power numbers in there, I still don't see Houser fully blowing up, and it should mean the Giants have a great shot to win another.

Pick: Giants ML (+250, FanDuel)


Giants vs Dodgers Weather


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About the Author

Kenny Ducey, a leading voice in tennis betting and MLB handicapping, has built an online following through his work for Tennis Channel and his background in baseball reporting for Sports Illustrated and Baseball Prospectus. With over a decade of experience, including covering the New York Knicks and Yankees for Fordham's WFUV Radio, Ducey writes betting previews for Action Network and contributes digitally to Tennis Channel, having also worked for NBC Sports and DraftKings.

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