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Giants vs Dodgers Prediction, Pick, Odds for Thursday, September 18

Giants vs Dodgers Prediction, Pick, Odds for Thursday, September 18 article feature image
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Darren Yamashita-Imagn Images. Pictured: Yoshinobu Yamamoto

The Los Angeles Dodgers host the San Francisco Giants on September 18, 2025. First pitch from Dodger Stadium is scheduled for 10:10 p.m. EDT; the game will be broadcast on SportsNet LA.

Find my MLB betting preview and Giants vs Dodgers prediction below, as well as probable pitchers, betting trends, injury reports and more.

Quickslip

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My Giants vs Dodgers Prediction

  • Giants vs Dodgers picks: Under 8 (-115 | Play to -120)

My Giants vs Dodgers best bet is Under 8. Make sure to find the best odds by checking our live MLB odds page.


Giants vs Dodgers Odds

Giants Logo
Thursday, Sep 18
10:10 p.m. ET
MLB Network
Dodgers Logo
Giants Odds
SpreadTotalMoneyline
+1.5
-160
8
100o / -120u
+140
Dodgers Odds
SpreadTotalMoneyline
-1.5
+135
8
100o / -120u
-165
Odds via bet365. Get up-to-the-minute MLB odds here.
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Giants vs Dodgers Projected Starting Pitchers

RHP Logan Webb (SFG)StatRHP Yoshinobu Yamamoto (LAD)
14-10W-L11-8
4.8fWAR (FanGraphs)4.7
3.34 / 3.72ERA /xERA2.66 / 2.69
2.71 / 2.79FIP / xFIP2.96 / 3.02
1.26WHIP0.98
20.7%K-BB%21.3%
54.3%GB%53.1%
104Stuff+97
108Location+110

Tony Sartori’s Giants vs Dodgers Preview

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San Francisco Giants Betting Preview: Logan's Webb

Logan Webb has put together yet another consistently solid campaign. Through 31 starts, Webb is 14-10 with a 3.34 ERA and 1.26 WHIP.

His underlying metrics are equally strong. Entering this matchup, the right-hander ranks in the 62nd percentile in expected ERA (xERA), 77th percentile in strikeout rate, and 91st percentile in walk rate.

Following Webb is one of the league’s strongest bullpens. This season, San Francisco’s relief corps ranks in the top four in ERA, xERA and FIP.

Despite the excellent pitching staff, the Giants have struggled this year due to their poor hitting. San Francisco currently ranks in the bottom 10 in hits per game, batting average, slugging percentage and OPS.


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Los Angeles Dodgers Betting Preview: Yamamoto Has Looked the Part

Those woes at the plate are likely to continue against Yoshinobu Yamamoto. Through 73 combined plate appearances against Yamamoto, this current Giants roster possesses a mere .152 batting average, .273 slugging percentage and .229 weighted on-base average (wOBA).

One of the best pitchers in the National League, Yamamoto boasts an 11-8 record with a 2.66 ERA and 0.98 WHIP through 28 appearances on the mound this year. His analytics are equally dominant.

Entering this matchup, Yamamoto ranks in the 95th percentile in xERA, 90th percentile in expected batting average (xBA), 88th percentile in strikeout rate and 86th percentile in barrel rate.

He also dominated San Francisco in each of the previous two meetings this season, posting a 0.64 ERA and 0.50 WHIP.

Like Webb, Yamamoto is followed by a solid bullpen. This season, Los Angeles’ relief corps ranks in the top 10 in xERA and WAR.


Giants vs Dodgers Prediction, Betting Analysis

The only concern with taking the under in this contest is the Dodgers’ powerhouse lineup. That said, Webb has proven he is capable of handling the task.

Meanwhile, Yamamoto has had no issue against the Giants. Each of those two aforementioned starts resulted in seven or fewer total runs scored.

Pick: Under 8 (-115 | Play to -120)


Moneyline

I lean toward Los Angeles, but I don't want to fade Webb.


Run Line (Spread)

I also like Los Angeles to cover, but I'm staying away for the same reason listed above.


Over/Under

As mentioned, I'm betting Under 8.


Giants vs Dodgers Betting Trends


Giants vs Dodgers Weather


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