Kentucky vs Iowa State Odds, Picks & Predictions - March 22, 2026

Kentucky at Iowa State

6:49 pm • CBS

Kentucky Wildcats

22-14

63 - 82

Iowa State Cyclones

29-8

MatchupOpenSpreadTotalMoneyline
Kentucky 22-14	+4.5	+5.5-112	o146.5-110	+185
Iowa State 29-8	u146	-5.5-107	u146.5-110	-225

Sunday 6:49 p.m.

March 22, 2026

Enterprise CenterSt. Louis

ISU -13.5 (Live)-164

0.24u

Over 77.5 (2H)-105

0.5u

ISU +100 (Live)

1.5u

ISU +1.5 (Live)-118

ISU +105 (Live)

0.42u

ISU -120 (Live)

0.17u

Boyd / FanDuel

UK +5.5-115

0.58u

Tailing @The_Oddsmaker

UK +207

$50.00

Pxpx

UK +5.5-110

0.55u

UK +195

0.5u

Outright or lose by 20

ISU -5-110

UK +5-110

Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy

Under 146.5-110

0.91u

Compete to the death

O.Oweh u23.5 Pts-120

$100.00

O.Oweh u20 Pts-101

0.99u

ISU -5.5-102

1.96u

D.Aberdeen o13.5 Pts-115

0.87u

ISU -5.5-105

1.9u

UK +5.5-115

0.58u

UK +5.5-115

0.58u

ISU -4.5-107

O.Oweh u23.5 Pts-115

0.87u

Under 146.5-110

UK +5-110

1.1u

C.Chandler o9.5 Pts-104

1.04u

O.Oweh u23.5 Pts-110

0.5u

Action Pro

UK +5-105

UK +190

UK +4.5-102

C.Chandler o9.5 Pts+170

$100.00

UK +5.5-113

1.13u

ISU -4.5-115

0.25u

Under 145.5-110

0.91u

UK +4.5-102

Under 146.5-115

0.87u

ISU -4.5-113

0.88u

UK +5.5-115

0.45u

Some speculation here but don’t think Jefferson plays which would make this a very good number to have in pocket

UK +5.5-115

$57.50

Half in for now

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NCAAB Public Betting

Iowa State are 3-2 in their last 5 games.
Iowa State are 4-1 in their last 5 games against the spread
Iowa State are 8-5 in their road games against the spread
The totals have gone OVER in 2 of Iowa State' last 5 games
The totals have gone OVER in 12 of Iowa State' 21 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Iowa State	20-14	12-9	8-5	15-9	2-1
Kentucky	17-17	10-12	7-5	7-8	6-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Iowa State	14-19-1	12-9	2-10-1	8-15-1	1-2
Kentucky	17-17	11-11	6-6	7-8	5-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Iowa State	29-8	N/A	N/A	19-5	1-2
Kentucky	22-14	N/A	N/A	11-4	3-9

date	opponent	score	spread	over/under	moneyline
Mar 20th	TNST	W 108-74	-25 W	O 147.5	ISU -10000
Mar 13th	@ARIZ	L 80-82	+3 W	O 144.5	ARIZ +142
Mar 12th	@TTU	W 75-53	-7 W	U 143.5	ISU -298
Mar 11th	ASU	W 91-42	-13.5 W	U 148.5	ISU -1200
Mar 7th	ASU	W 86-65	-16.5 W	O 148.5	ISU -2100

Kentucky

Iowa State

21-45 (47%)

Field Goals

28-61 (46%)

12-17 (71%)

Free Throws

17-24 (71%)

9-25 (36%)

9-28 (32%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

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MatchupOverUnder
Kentucky 22-14	N/A	N/A
Iowa State 29-8	N/A	N/A

Kentucky vs. Iowa State Odds & Betting Predictions - March 22, 2026

Kentucky at Iowa State

Kentucky Wildcats

Iowa State Cyclones

Kentucky at Iowa State Odds

Spread, Total, Moneyline

Kentucky vs. Iowa State Previews & Analysis

Kentucky vs Iowa State: Over/Under Pick for Sunday Night

NCAAB Player Props for Sunday's 2nd-Round Games

+1277 Pace Trend Parlay (Thursday's Hit!)

Solid Edge on This Total & More Sunday March Madness Bets

Prop Odds Comparison

Line Movement Tracker

Kentucky vs. Iowa State Public Betting Percentages

Kentucky

Public

Iowa State

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

Kentucky vs. Iowa State Odds Comparison

Kentucky at Iowa State Team Totals