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Kentucky vs. Vanderbilt Odds & Betting Predictions - November 22, 2025

Kentucky at Vanderbilt

8:30 pm • ESPN

Kentucky Wildcats

6-1
17
17 - 45

Vanderbilt Commodores

3-4
45

Kentucky at Vanderbilt Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Kentucky
6-1
+8.5
+7-113
o53.5-113
+225
Vanderbilt
3-4
u53.5
-7-106
u53.5-108
-290
location pinSaturday 8:30 p.m.
November 22, 2025
FirstBank StadiumNashville
Kentucky vs. Vanderbilt Expert Picks
Doug Ziefel
Doug Ziefel
Last 30d: 358-379-7 (+18.3u)
C.Boley u29.5 Pass Att-110
0.55u
Duck
Duck
Last 30d: 83-65-2 (+5.1u)
Under 53.5-110
1.1u
Mike Calabrese
Mike Calabrese
Last 30d: 37-52-0 (+0.3u)
VAN -8.5-108
2.78u
🎵 Diego, Diego 🎵
Brian Bitler
Brian Bitler
Last 30d: 68-78-4 (-25.5u)
UK +8.5-109
3u
Sir Lockselot
Sir Lockselot
Last 30d: 13-34-0 (-5.3u)
UK +7.5-112
2u
📚Player Profit 🔑 Kentucky +7.5 -112 (Player Profit) 2u Kentucky is on a bit of a roll winning 3 straight. 4-3 ATS as dogs this season. Expecting a tight game Code: sirlocks for 10% off when you get funded at https://www.playerprofit.com/

Kentucky vs. Vanderbilt Previews & Analysis

  • Collin's Thoughts On Kentucky-Vanderbilt article feature image

    Collin's Thoughts On Kentucky-Vanderbilt

    Collin Wilson•
    Nov 22, 2025 UTC
  • Your Week 13 NCAAF Betting Cheat Sheet article feature image

    Your Week 13 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Nov 22, 2025 UTC
  • Line-Move Model's Surprise Upset Picks article feature image

    Line-Move Model's Surprise Upset Picks

    Alex Kolodziej•
    Nov 22, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Kentucky vs. Vanderbilt Public Betting Percentages

Away Logo

Kentucky

Public

Home Logo

Vanderbilt

53%

Bets%

47%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Vanderbilt are 2-3 in their last 5 games.
  • Vanderbilt are 2-3 in their last 5 games against the spread
  • Vanderbilt are 2-0 in their road games against the spread
  • The totals have gone OVER in 3 of Vanderbilt' last 5 games
  • The totals have gone OVER in 4 of Vanderbilt' 5 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Vanderbilt		3-41-42-01-32-1
Kentucky		6-13-13-02-04-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Vanderbilt		5-24-11-13-12-1
Kentucky		5-23-12-11-14-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Vanderbilt		3-4N/AN/A3-10-3
Kentucky		6-1N/AN/A2-04-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 8thAUBW 45-38-6 WO 46.5VAN -234
Nov 1st@TEXL 31-34+3.5 WO 48TEX +145
Oct 25thMIZW 17-10-3 WU 52.5VAN -155
Oct 18thLSUW 31-24-1.5 WO 48.5VAN -120
Oct 4th@BAMAL 14-30+12.5 LU 57.5BAMA +385
Team Stats

Total

315
Total Yards
604
68
Total Plays
69
4.632352941176471
Yards Per Play
8.753623188405797

Passing

284
YDS
539
29/49
Comps/Atts
37/44
5.795918367346939
YPA
12.25
2/3
TDs/INTs
5/1
2/12
Sacks/Yards
4/16

Rushing

31
Rush Yards
65
19
Attempts
25
1.631578947368421
YPC
2.6
0
TDs
1

Turnovers

0
Fumbles Lost
0
3
Interceptions
1

Efficiency

1/2 50%
Redzone
4/5 80%
6/15 0%
3rd Down
3/9 0%
1/1 0%
4th Down
2/4 0%

First Downs

18
Total
29
16
Pass
22
2
Rush
5
0
Penalty
2

Misc

7/65
Penalties/Yards
7/70

Kentucky vs. Vanderbilt Odds Comparison

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Kentucky at Vanderbilt Team Totals

MatchupOverUnder
Kentucky
6-1
N/A
N/A
Vanderbilt
3-4
N/A
N/A