Welcome to Week 6 of the college football season.
For the eighth straight season on our college football betting podcast, Big Bets on Campus, Collin Wilson and Stuckey pick their two favorite moneyline underdogs for each week's slate.
For Week 6 of the season, they're rolling with two very different underdogs. One 'dog is of the Group of 5 variety, while the other is a ranked ACC squad in one of the biggest matchups of the day.
If you're feeling lucky, a parlay of both pups pays out around 4-1 at the time of writing.
Let's dive into our college football moneyline underdogs for Week 6.
- 2018-24: 85-129, +15.91 Units
- 2025: 4-6, -0.2 Units
- Overall: 89-135, +15.71 Units
College Football Moneyline Underdog Picks
Collin Wilson: South Alabama ML -105 vs. Troy
South Alabama Odds | ||
---|---|---|
Spread | Total | Moneyline |
+1 -110 | 47.5 -110o / -110u | -110 |
Troy Odds | ||
---|---|---|
Spread | Total | Moneyline |
-1 -110 | 47.5 -110o / -110u | -110 |
This handicap is quite simple: Troy is a complete fraud.
The Trojans' only two wins this season have come against FCS Nicholls and a MAC foe in Buffalo, and they lost the box score against the Bulls.
With a 17-0 lead heading into the fourth quarter, Buffalo had a 99% chance to win, according to the Action Network App.

Troy also went 3-for-4 on fourth downs, while Buffalo went 0-for-1. The Trojans ran for just 3.5 yards per carry and completed just over half of their passes.
They put up a fight against Clemson early in the season, but the Tigers have proven to be a mess thus far.
This Troy team is a complete fraud. It's a broken team. Give me South Alabama.
Stuckey: Florida State ML +160 vs. Miami
Miami Odds | ||
---|---|---|
Spread | Total | Moneyline |
-4 -110 | 54 -110o / -110u | -190 |
Florida State Odds | ||
---|---|---|
Spread | Total | Moneyline |
+4 -110 | 54 -110o / -110u | +160 |
I took the 4.5 points with Florida State, and the Seminoles are my top underdog as well.
I don’t see a huge edge, as my numbers make this spread closer to a field goal. I have Miami power-rated as the fifth-best team in the country, but it's possible we're overrating the Canes a bit.
Their offensive line is one of the best in the nation, and they have two of the best defensive ends in Akheem Mesidor and Rueben Bain. That’s a serious front.
I downgraded Florida State a bit after last week even though it should have won that game with a 60-70% win probability. But it feels like FSU got caught peeking ahead and looking toward the Hurricanes.
Right now, I only have Miami as a field goal favorite, and this is its first road game of the year.
The Canes have looked impressive, but when adjusting for their opponents, their offense doesn’t quite look like a top-five unit.
Plus, they benefited from playing Notre Dame and CJ Carr at home in his first road start, took advantage of South Florida when it was drained in what might've been the best situational spot of the season to this point and faced a broken Florida team.
That schedule has given them some easy spots that might be inflating their rating a bit.
Miami ranks top-five in my book, but I still see value on Florida State. And don’t forget, this will be Carson Beck’s first road start with the Canes, which could end up being a factor.