The Wyoming Cowboys take on the San Diego State Aztecs in San Diego, California. Kickoff is set for 7 p.m. ET on CBS Sports Network.
San Diego State is favored by -10.5 points on the spread with a moneyline of -450. The total is set at 42.5 points.
Here’s my Wyoming vs. San Diego State prediction and college football picks for Saturday, November 1.
Wyoming vs San Diego State Prediction
- Wyoming vs. San Diego State Pick: San Diego State -10.5 (-110, bet365)
My San Diego State vs. Wyoming best bet is on the Aztecs. Find the best line available on our live NCAAF odds page.
Wyoming vs San Diego State Odds
| Wyoming Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+10.5 -110 | 42 -110o / -110u | +325 |
| San Diego St Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-10.5 -110 | 42 -110o / -110u | -425 |
- Wyoming vs San Diego State point spread: San Diego State -10.5 (-110), Wyoming +10.5 (-110)
- Wyoming vs San Diego State over/under: 42 (-110o / -110u).
- Wyoming vs San Diego State moneyline: Wyoming +325, San Diego State -425
Wyoming vs San Diego State Preview
I’m laying the points with San Diego State.
I’m not overly impressed with Wyoming. The Cowboys have faced two of the Mountain West’s worst defenses over the past two weeks, and they’ll be playing the league’s best this week.
San Diego State leads the conference in PFF’s Rush Defense grades, Tackling grades, Coverage grades, and Special Teams grades. The Aztecs are allowing just 88 rushing yards per game at 2.7 yards per rush.
At the same time, San Diego State has rushed for over 200 yards in three straight weeks. Jayden Denegal��s emergence as a passer has unlocked the offense.
Wyoming has no pass rush, ranking 131st nationally in Havoc. Denegal will have the time in the world to go through his progressions, let the routes develop, and throw it all over the field.
Wyoming wants to run the ball, but the Pokes aren’t very explosive. I don’t foresee them running the ball on San Diego State, which will force Kaden Anderson to beat the defense through the air — and that also won’t happen, considering the Aztecs can blanket Wyoming’s two most explosive receivers.
Pick: San Diego State -10.5 (-110, bet365)



















